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    ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 [ Homo sapiens (human) ]

    Gene ID: 955, updated on 28-Oct-2024

    Summary

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    Official Symbol
    ENTPD6provided by HGNC
    Official Full Name
    ectonucleoside triphosphate diphosphohydrolase 6provided by HGNC
    Primary source
    HGNC:HGNC:3368
    See related
    Ensembl:ENSG00000197586 MIM:603160; AllianceGenome:HGNC:3368
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CD39L2; IL6ST2; IL-6SAG; NTPDase-6; dJ738P15.3
    Summary
    ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
    Expression
    Ubiquitous expression in prostate (RPKM 15.7), colon (RPKM 15.3) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ENTPD6 in Genome Data Viewer
    Location:
    20p11.21
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (25195712..25228075)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (25260296..25293060)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (25176348..25208711)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC284798 Neighboring gene Sharpr-MPRA regulatory region 10160 Neighboring gene NIPAL1 pseudogene 1 Neighboring gene uncharacterized LOC101926889 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17660 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12741 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17661 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17662 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17663 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:25194425-25194926 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:25202205-25202966 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:25202967-25203726 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:25203727-25204488 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:25204539-25204720 Neighboring gene uncharacterized LOC105372579 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17664 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12742 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr20:25218064-25219263 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr20:25222455-25223072 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:25227753-25228006 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12743 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12744 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12745 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17665 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12746 Neighboring gene glycogen phosphorylase B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:25274716-25275238 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:25276284-25276805 Neighboring gene abhydrolase domain containing 12, lysophospholipase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. CD39L2, a gene encoding a human nucleoside diphosphatase, predominantly expressed in the heart. Yeung G, et al. Biochemistry, 2000 Oct 24. PMID 11041856
    2. Expression and characterization of soluble and membrane-bound human nucleoside triphosphate diphosphohydrolase 6 (CD39L2). Hicks-Berger CA, et al. J Biol Chem, 2000 Nov 3. PMID 10948193
    3. Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: implications for structure and function. Ivanenkov VV, et al. Biochemistry, 2003 Oct 14. PMID 14529283
    4. Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes. Chadwick BP, et al. Mamm Genome, 1997 Sep. PMID 9271669
    5. The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster. Chadwick BP, et al. Genomics, 1998 Jun 15. PMID 9676430

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
      Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
    2. Observational study of gene-disease association. (HuGE Navigator)
      Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
    3. A secondary structural model of NTPDase-6 is proposed based on disulfide architecture (four conserved cysteine residues Cys249-Cys280 and Cys340-Cys354, circular dichroism data, and regions of conservation among all NTPDases.
      Title: Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: implications for structure and function.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ36711, dJ738P15.3,, DKFZp781G2277, DKFZp781K21102

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables CDP phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GDP phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GDP phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables IDP phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleoside diphosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ribonucleoside triphosphate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleoside diphosphate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to calcium ion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to magnesium ion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    		  
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ectonucleoside triphosphate diphosphohydrolase 6
    Names
    CD39 antigen-like 2
    NTPDase 6
    ectonucleoside triphosphate diphosphohydrolase 6 (putative)
    interleukin 6 signal transducer-2
    NP_001107561.2
    NP_001238.3
    NP_001304870.2
    NP_001309307.2
    NP_001309308.1
    NP_001309309.1
    NP_001309310.1
    NP_001309311.1
    NP_001309312.1
    NP_001309313.1
    NP_001309314.2
    NP_001309315.2
    NP_001309316.2
    NP_001309317.2
    NP_001309318.2
    NP_001309319.2
    NP_001309320.2
    NP_001309321.2
    NP_001309322.2
    NP_001309323.2
    NP_001309324.2
    NP_001309325.2
    NP_001309326.2
    NP_001309327.2
    XP_016883622.1
    XP_016883623.1
    XP_047296547.1
    XP_047296548.1
    XP_047296549.1
    XP_047296550.1
    XP_047296551.1
    XP_047296552.1
    XP_047296553.1
    XP_047296554.1
    XP_047296555.1
    XP_047296556.1
    XP_054180205.1
    XP_054180206.1
    XP_054180207.1
    XP_054180208.1
    XP_054180209.1
    XP_054180210.1
    XP_054180211.1
    XP_054180212.1
    XP_054180213.1
    XP_054180214.1
    XP_054180215.1
    XP_054180216.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114089.4 → NP_001107561.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an internal exon in the 5' region, resulting in a distinct 5' UTR and the use of an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus, and is shorter than isoform 1.
      Source sequence(s)
      AL035252
      Consensus CDS
      CCDS46586.1
      UniProtKB/TrEMBL
      B4E1D1
      Related
      ENSP00000347084.5, ENST00000354989.9
      Conserved Domains (1) summary
      cl17037
      Location:78 → 460
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. NM_001247.5 → NP_001238.3  ectonucleoside triphosphate diphosphohydrolase 6 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AL035252
      Consensus CDS
      CCDS13170.1
      UniProtKB/Swiss-Prot
      A6NCX6, D3DW49, O75354, Q5QPJ2, Q5QPJ5, Q7Z5B5, Q8N3H3, Q8TAS7, Q9UJD1
      UniProtKB/TrEMBL
      B4E1D1
      Related
      ENSP00000365840.4, ENST00000376652.9
      Conserved Domains (1) summary
      cl17037
      Location:95 → 477
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    3. NM_001317941.3 → NP_001304870.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AL035252
      Consensus CDS
      CCDS82604.1
      UniProtKB/TrEMBL
      B4E1D1
      Related
      ENSP00000353131.2, ENST00000360031.6
      Conserved Domains (1) summary
      cl17037
      Location:94 → 476
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    4. NM_001322378.2 → NP_001309307.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL035252
      Consensus CDS
      CCDS13170.1
      UniProtKB/Swiss-Prot
      A6NCX6, D3DW49, O75354, Q5QPJ2, Q5QPJ5, Q7Z5B5, Q8N3H3, Q8TAS7, Q9UJD1
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:95 → 477
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    5. NM_001322379.2 → NP_001309308.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DHS2, B4DU64
      Conserved Domains (1) summary
      cl17037
      Location:1 → 225
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    6. NM_001322380.2 → NP_001309309.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      H0Y3D0
      Conserved Domains (1) summary
      cl17037
      Location:1 → 178
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    7. NM_001322381.2 → NP_001309310.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      H0Y3D0
      Conserved Domains (1) summary
      cl17037
      Location:1 → 178
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    8. NM_001322382.2 → NP_001309311.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DU64
      Conserved Domains (1) summary
      cl17037
      Location:1 → 259
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    9. NM_001322383.2 → NP_001309312.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DU64
      Conserved Domains (1) summary
      cl17037
      Location:1 → 259
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    10. NM_001322384.2 → NP_001309313.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DU64
      Conserved Domains (1) summary
      cl17037
      Location:1 → 259
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    11. NM_001322385.2 → NP_001309314.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:78 → 412
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    12. NM_001322386.2 → NP_001309315.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:78 → 426
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    13. NM_001322387.2 → NP_001309316.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:95 → 429
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    14. NM_001322388.2 → NP_001309317.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AL035252
      Consensus CDS
      CCDS82603.1
      UniProtKB/TrEMBL
      B4DNK6, Q5QPI9
      Related
      ENSP00000401895.2, ENST00000433259.6
      Conserved Domains (1) summary
      cl17037
      Location:95 → 303
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    15. NM_001322389.2 → NP_001309318.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:92 → 440
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    16. NM_001322390.2 → NP_001309319.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:95 → 443
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    17. NM_001322391.2 → NP_001309320.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:95 → 443
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    18. NM_001322392.2 → NP_001309321.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DDM7
      Conserved Domains (1) summary
      cl17037
      Location:77 → 378
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    19. NM_001322393.2 → NP_001309322.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DDM7
      Conserved Domains (1) summary
      cl17037
      Location:78 → 379
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    20. NM_001322394.2 → NP_001309323.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:77 → 459
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    21. NM_001322395.2 → NP_001309324.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DDM7
      Conserved Domains (1) summary
      cl17037
      Location:92 → 393
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    22. NM_001322396.2 → NP_001309325.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DNK6
      Conserved Domains (1) summary
      cl17037
      Location:94 → 395
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    23. NM_001322397.2 → NP_001309326.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 18

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4DNK6
      Conserved Domains (1) summary
      cl17037
      Location:95 → 396
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    24. NM_001322398.2 → NP_001309327.2  ectonucleoside triphosphate diphosphohydrolase 6 isoform 19

      Status: REVIEWED

      Source sequence(s)
      AL035252
      UniProtKB/TrEMBL
      B4E1D1
      Conserved Domains (1) summary
      cl17037
      Location:92 → 474
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      25195712..25228075
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047440595.1 → XP_047296551.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X4

      Conserved Domains (1) summary
      cl17037
      Location:92 → 393
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. XM_047440594.1 → XP_047296550.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X3

    3. XM_047440597.1 → XP_047296553.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X6

    4. XM_047440596.1 → XP_047296552.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X5

      Conserved Domains (1) summary
      cl17037
      Location:92 → 440
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    5. XM_047440598.1 → XP_047296554.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X7

    6. XM_017028133.3 → XP_016883622.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X8

      UniProtKB/TrEMBL
      B4DDM7

    7. XM_017028134.2 → XP_016883623.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X11

    8. XM_047440599.1 → XP_047296555.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X9

    9. XM_047440591.1 → XP_047296547.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X1

      UniProtKB/Swiss-Prot
      A6NCX6, D3DW49, O75354, Q5QPJ2, Q5QPJ5, Q7Z5B5, Q8N3H3, Q8TAS7, Q9UJD1

    10. XM_047440592.1 → XP_047296548.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X2

    11. XM_047440593.1 → XP_047296549.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X2

    12. XM_047440600.1 → XP_047296556.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X10

      Related
      ENSP00000365854.3, ENST00000376666.3

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      25260296..25293060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054324234.1 → XP_054180209.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X4

    2. XM_054324233.1 → XP_054180208.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X3

    3. XM_054324236.1 → XP_054180211.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X6

    4. XM_054324235.1 → XP_054180210.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X5

    5. XM_054324237.1 → XP_054180212.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X7

    6. XM_054324238.1 → XP_054180213.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X8

    7. XM_054324241.1 → XP_054180216.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X11

    8. XM_054324239.1 → XP_054180214.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X9

    9. XM_054324230.1 → XP_054180205.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X1

    10. XM_054324231.1 → XP_054180206.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X2

    11. XM_054324232.1 → XP_054180207.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X2

    12. XM_054324240.1 → XP_054180215.1  ectonucleoside triphosphate diphosphohydrolase 6 isoform X10

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O75354.3 GenPept UniProtKB/Swiss-Prot:O75354

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