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    Rpph1 ribonuclease P RNA component H1 [ Mus musculus (house mouse) ]

    Gene ID: 85029, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Rpph1provided by MGI
    Official Full Name
    ribonuclease P RNA component H1provided by MGI
    Primary source
    MGI:MGI:1934664
    See related
    Ensembl:ENSMUSG00000092837 AllianceGenome:MGI:1934664
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpr; H1RNA; Rmrp5; Gm24821
    Summary
    Orthologous to human RPPH1 (ribonuclease P RNA component H1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See Rpph1 in Genome Data Viewer
    Location:
    14 C1; 14 26.25 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51044904..51045228, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (50807447..50807771, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 5 Neighboring gene cyclin B1 interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E753 Neighboring gene poly (ADP-ribose) polymerase family, member 2 Neighboring gene telomerase associated protein 1 Neighboring gene predicted gene, 52116

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Long non-coding RNA Rpph1 promotes inflammation and proliferation of mesangial cells in diabetic nephropathy via an interaction with Gal-3. Zhang P, et al. Cell Death Dis, 2019 Jul 8. PMID 31285427, Free PMC Article
    2. A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. structure and expression of the mouse PARP-2 gene. Ame JC, et al. J Biol Chem, 2001 Apr 6. PMID 11133988
    3. RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis. Cerritelli SM, et al. Curr Genet, 2020 Dec. PMID 32886170, Free PMC Article
    4. Nucleotide sequences of the RNA subunit of RNase P from several mammals. Altman S, et al. Genomics, 1993 Nov. PMID 7507079
    5. Cloning and characterization of three new murine genes encoding short homologues of RNase P RNA. Li K, et al. J Biol Chem, 1995 Oct 20. PMID 7559668

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis.
      Title: RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis.
    2. These results provide new insight into the association between Rpph1 and the Gal-3/Mek/Erk signaling pathway during diabetic nephropathy progression.
      Title: Long non-coding RNA Rpph1 promotes inflammation and proliferation of mesangial cells in diabetic nephropathy via an interaction with Gal-3.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Other Names

    • RNA component of nuclear RNAase P, 5
    • RNase P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002142.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC027184
      Related
      ENSMUST00000175096.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      51044904..51045228 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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