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    Pramel26 PRAME like 26 [ Mus musculus (house mouse) ]

    Gene ID: 381569, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Pramel26provided by MGI
    Official Full Name
    PRAME like 26provided by MGI
    Primary source
    MGI:MGI:3650237
    See related
    Ensembl:ENSMUSG00000059218 AllianceGenome:MGI:3650237
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13084
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in 2-cell stage embryo. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Pramel26 in Genome Data Viewer
    Location:
    4 E1; 4 77.97 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (143535817..143542663, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (143809245..143816093, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene PRAME like 24 Neighboring gene PRAME like 25 Neighboring gene PRAME like 27 Neighboring gene STARR-seq mESC enhancer starr_11975 Neighboring gene STARR-seq mESC enhancer starr_11976 Neighboring gene PRAME like 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte. Dadé S, et al. FEBS Lett, 2003 Dec 18. PMID 14675769
    2. Deterministic and stochastic allele specific gene expression in single mouse blastomeres. Tang F, et al. PLoS One, 2011. PMID 21731673, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Clone Names

    • MGC91195

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    oogenesin-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005371.4 → NP_001005371.3  oogenesin-like isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL626771
      Consensus CDS
      CCDS38948.1
      UniProtKB/TrEMBL
      A2A8N0
      Related
      ENSMUSP00000074557.5, ENSMUST00000075045.4

    2. NM_001347257.2 → NP_001334186.2  oogenesin-like isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL626771
      Consensus CDS
      CCDS84819.1
      UniProtKB/TrEMBL
      A6PWA3
      Related
      ENSMUSP00000101395.3, ENSMUST00000105769.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      143535817..143542663 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253637.1 → XP_030109497.1  oogenesin-like isoform X1

      UniProtKB/TrEMBL
      Q66JS9

    2. XM_017320294.1 → XP_017175783.1  oogenesin-like isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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