Grip1 glutamate receptor interacting protein 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Grip1provided by MGI
Official Full Name: glutamate receptor interacting protein 1provided by MGI
Primary source: MGI:MGI:1921303
See related: Ensembl:ENSMUSG00000034813 AllianceGenome:MGI:1921303
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: eb; GRIP; 4931400F03Rik
Summary: This gene encodes a protein containing multiple PDZ (post synaptic density protein, Drosophila disc large tumor suppressor, and zonula occludens-1 protein) domains. The encoded protein acts as a mediator between cytoskeletal and membrane proteins, particularly in neuronal cells, and facilitates complex formation at the cell membrane. Mutation of this gene can cause embryonic lethality resulting from defects of the dermo-epidermal junction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Expression: Biased expression in testis adult (RPKM 9.5), CNS E18 (RPKM 3.2) and 8 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 10 D2; 10 67.33 cM

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (119289810..119923172)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (119453238..120087267)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Glutamate Receptor Interacting Protein 1 in the Dorsal CA1 Drives Alpha-amino-3-hydroxy-5-methyl-4-Isoxazolepropionic Acid Receptor Endocytosis and Exocytosis Bidirectionally and Mediates Forgetting, Exploratory, and Anxiety-like Behavior.
Title: Glutamate Receptor Interacting Protein 1 in the Dorsal CA1 Drives Alpha-amino-3-hydroxy-5-methyl-4-Isoxazolepropionic Acid Receptor Endocytosis and Exocytosis Bidirectionally and Mediates Forgetting, Exploratory, and Anxiety-like Behavior.
EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity.
Title: EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity.
GRIP1 regulates synaptic plasticity and learning and memory.
Title: GRIP1 regulates synaptic plasticity and learning and memory.
Results indicate that loss of Grip1/2 in cerebellar Purkinje cells contributes to increased repetitive self-grooming, a core autism behavior in mice
Title: Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum.
study demonstrates that conditional deletion of GRIP1 in the medial prefrontal cortex increases the motivation for cocaine and potentiates cue-induced reinstatement of cocaine seeking in male and female mice.
Title: Glutamate receptor interacting protein acts within the prefrontal cortex to blunt cocaine seeking.
GRIP1 is phosphorylated at an N-terminal serine cluster by cyclin-dependent kinase-9 (CDK9), which is recruited into GC-induced GR:GRIP1:CDK9 hetero-complexes, producing distinct GRE-specific GRIP1 phospho-isoforms.
Title: Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages.
GRIP1 is a critical regulator of immunometabolism, which engages distinct transcriptional mechanisms to coordinate the balance between macrophage populations and ultimately promote metabolic homeostasis.
Title: The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis.
Data suggest that molecules in the erythropoietin-producing hepatocellular receptor B family (EPHB) / ephrinB (EFNB) signalling pathways, specifically ephrin B3 and GRIP1, are involved blood pressure regulation.
Title: The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility.
GRIP1 binds to apoER2 and EphrinB2 to induce activity-dependent AMPA receptor insertion at the synapse.
Title: GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.
Study performed social behavioral testing on neuron-specific Grip1/2-double knockout (DKO) and wild type (WT) mice and determined the expression profile of key signaling proteins in AMPAR, mGluR, mTOR, and GABA pathways in brain. Data Grip1/2-mediated AMPA signaling in regulating social behaviors and disturbance of glutamate- and GABA-signaling in specialized brain regions in autism-related social behavioral deficits.
Title: Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880.

Submit: New GeneRIF Correction See all GeneRIFs (21)

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Spontaneous (1)
Targeted (3) 1 citation

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

D10Ertd584e (e-PCR), detects polymorphism
- UniSTS:167021

PMC124486P1 (e-PCR)
- UniSTS:270471

D10Mit187 (e-PCR), detects polymorphism
- UniSTS:126087

D10Mit204 (e-PCR), detects polymorphism
- UniSTS:126105

NoName (e-PCR)
- UniSTS:236472

D10Mit237 (e-PCR), detects polymorphism
- UniSTS:126142

D10Mit267 (e-PCR), detects polymorphism
- UniSTS:126172

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables GTPase binding	ISO Inferred from Sequence Orthology more info
enables PDZ domain binding	ISO Inferred from Sequence Orthology more info
enables ionotropic glutamate receptor binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables signaling receptor binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular response to brain-derived neurotrophic factor stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to phorbol 13-acetate 12-myristate	ISO Inferred from Sequence Orthology more info
involved_in dendrite arborization	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	ISO Inferred from Sequence Orthology more info
involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane	IEP Inferred from Expression Pattern more info	PubMed
involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of dendrite morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neuron projection arborization	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of synaptic scaling	ISO Inferred from Sequence Orthology more info
involved_in vesicle-mediated transport in synapse	IDA Inferred from Direct Assay more info	PubMed
involved_in vesicle-mediated transport in synapse	IEP Inferred from Expression Pattern more info	PubMed
involved_in vesicle-mediated transport in synapse	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in GABA-ergic synapse	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in dendrite	IEA Inferred from Electronic Annotation more info
located_in dendrite	ISO Inferred from Sequence Orthology more info
located_in dendritic shaft	ISO Inferred from Sequence Orthology more info
located_in dendritic spine	ISO Inferred from Sequence Orthology more info
located_in dendritic spine head	ISO Inferred from Sequence Orthology more info
located_in dendritic spine neck	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
part_of exocyst	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	IEP Inferred from Expression Pattern more info	PubMed
is_active_in glutamatergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in membrane raft	IDA Inferred from Direct Assay more info	PubMed
located_in microtubule	ISO Inferred from Sequence Orthology more info
located_in neuron projection	IDA Inferred from Direct Assay more info	PubMed
located_in neuronal cell body	ISO Inferred from Sequence Orthology more info
located_in perikaryon	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in postsynapse	ISO Inferred from Sequence Orthology more info
located_in postsynapse	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	IEA Inferred from Electronic Annotation more info
is_active_in postsynaptic density	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	ISO Inferred from Sequence Orthology more info
located_in postsynaptic membrane	IEA Inferred from Electronic Annotation more info
located_in postsynaptic membrane	ISO Inferred from Sequence Orthology more info
located_in presynapse	ISO Inferred from Sequence Orthology more info
located_in presynaptic active zone	ISO Inferred from Sequence Orthology more info
located_in presynaptic membrane	ISO Inferred from Sequence Orthology more info
located_in proximal dendrite	ISO Inferred from Sequence Orthology more info
located_in recycling endosome	ISO Inferred from Sequence Orthology more info
located_in spine synapse	ISO Inferred from Sequence Orthology more info
located_in synaptic cleft	ISO Inferred from Sequence Orthology more info
located_in synaptic membrane	ISO Inferred from Sequence Orthology more info
located_in terminal bouton	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: glutamate receptor-interacting protein 1

Names: eye blebs

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277292.1 → NP_001264221.1 glutamate receptor-interacting protein 1 isoform 4

Status: REVIEWED

Description

Transcript Variant: This variant (4) contains multiple differences, compared to variant 1, including the lack of multiple exons. It represents use of an alternate promoter and initiates translation at an alternate start codon. The encoded isoform (4) is shorter and has a distinct N-terminus, compared to isoform 1.

Source sequence(s)

AC134326, AC162467, AK016420, AK043821, BC072632

Consensus CDS

CCDS70112.1

UniProtKB/TrEMBL

H7BX09, Q5DTG7

Related

ENSMUSP00000042436.9, ENSMUST00000041962.16

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_001277293.1 → NP_001264222.1 glutamate receptor-interacting protein 1 isoform 5

See identical proteins and their annotated locations for NP_001264222.1

Status: REVIEWED

Description

Transcript Variant: This variant (5) contains multiple differences at both the 5' and 3' ends, compared to variant 1. These differences include initiation of translation at an alternate start codon and use of an alternate 3' exon structure. The encoded isoform (5) is shorter and has distinct N- and C- termini, compared to isoform 1.

Source sequence(s)

AC162467, BC072632

Consensus CDS

CCDS70111.1

UniProtKB/TrEMBL

D3Z6T4, Q6GQT7

Related

ENSMUSP00000115478.2, ENSMUST00000147356.9

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_001277294.1 → NP_001264223.1 glutamate receptor-interacting protein 1 isoform 6

Status: REVIEWED

Description

Transcript Variant: This variant (6) lacks two alternate in-frame exons, compared to variant 1. The encoded isoform (6) is shorter than isoform 1.

Source sequence(s)

AB051560, AB051561, AC134326, AC153493, AK043821

Consensus CDS

CCDS70113.1

UniProtKB/TrEMBL

H7BX90, Q6NWW3

Related

ENSMUSP00000100897.3, ENSMUST00000105262.9

Conserved Domains (1) summary

cd00992
Location:152 → 235

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_001277295.1 → NP_001264224.1 glutamate receptor-interacting protein 1 isoform 7

Status: REVIEWED

Description

Transcript Variant: This variant (7) contains multiple differences compared to variant 1, including the lack of multiple exons. It represents use of an alternate promoter and initiates translation at an alternate start codon. The encoded isoform (7, also known as tau) is shorter and has a distinct N-terminus, compared to isoform 1. This isoform is localized to the nucleus (PMID: 15507123).

Source sequence(s)

AC134326, AK029905, AK043821

Consensus CDS

CCDS70114.1

UniProtKB/TrEMBL

Q6X4T6

Related

ENSMUSP00000100896.3, ENSMUST00000105261.9

Conserved Domains (1) summary

cd00992
Location:255 → 336

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_001358809.1 → NP_001345738.1 glutamate receptor-interacting protein 1 isoform 8

Status: REVIEWED

Source sequence(s)

AB051561, AC134326, AC162467, AK043821, BC072632, CB524852, CJ056489, CV559946

UniProtKB/TrEMBL

Q5DTG7

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_001358810.1 → NP_001345739.1 glutamate receptor-interacting protein 1 isoform 9

Status: REVIEWED

Source sequence(s)

AB051561, AC153493, AK039673, BC072632

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_001358811.1 → NP_001345740.1 glutamate receptor-interacting protein 1 isoform 10

Status: REVIEWED

Source sequence(s)

AB051561, AC134326, AC153493, AK043821

UniProtKB/TrEMBL

D3YZL8

Conserved Domains (1) summary

cd00992
Location:182 → 265

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_028736.2 → NP_083012.1 glutamate receptor-interacting protein 1 isoform 1

See identical proteins and their annotated locations for NP_083012.1

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the isoform (1, also known as 1a-long).

Source sequence(s)

AB051561, AC134326, AC153493, AK043821

Consensus CDS

CCDS24202.1

UniProtKB/Swiss-Prot

Q8BLQ3, Q8C0T3, Q925T5, Q925T6, Q925T7

UniProtKB/TrEMBL

D3YZL8

Related

ENSMUSP00000123234.2, ENSMUST00000138410.8

Conserved Domains (1) summary

cd00992
Location:152 → 235

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_130891.2 → NP_570961.1 glutamate receptor-interacting protein 1 isoform 2

See identical proteins and their annotated locations for NP_570961.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks two alternate in-frame exons, compared to variant 1. The encoded isoform (2, also known as 1a-short) is shorter than isoform 1.

Source sequence(s)

AB051560, AC134326, AC153493, AK043821

Consensus CDS

CCDS36072.1

UniProtKB/TrEMBL

Q6NWW3

Related

ENSMUSP00000121670.2, ENSMUST00000144825.8

Conserved Domains (1) summary

cd00992
Location:125 → 208

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
NM_133442.2 → NP_597699.1 glutamate receptor-interacting protein 1 isoform 3

See identical proteins and their annotated locations for NP_597699.1

Status: REVIEWED

Description

Transcript Variant: This variant (3) contains multiple differences, compared to variant 1, including the lack of multiple exons. It represents use of an alternate promoter and initiates translation at an alternate start codon. The encoded isoform (3, also known as 1b-short) is shorter and has a distinct N-terminus, compared to isoform 1.

Source sequence(s)

AB051562, AC134326, AC162467, AK043821, BC072632

Consensus CDS

CCDS36071.1

UniProtKB/TrEMBL

Q5DTG7

Related

ENSMUSP00000077033.7, ENSMUST00000077871.14

Conserved Domains (1) summary

cd00992
Location:126 → 209

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RNA

NR_102387.1 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (8) contains multiple differences at both the 5' and 3' ends, compared to variant 1. This variant is represented as non-coding because the use of the expected translational start codon used in variant 7 renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC134326, AK029905, BC072632

Related

ENSMUST00000081260.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000076.7 Reference GRCm39 C57BL/6J

Range

119289810..119923172

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036156052.1 → XP_036011945.1 glutamate receptor-interacting protein 1 isoform X14

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514238.4 → XP_006514301.1 glutamate receptor-interacting protein 1 isoform X10

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156059.1 → XP_036011952.1 glutamate receptor-interacting protein 1 isoform X23

UniProtKB/TrEMBL

Q5DTG7

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156057.1 → XP_036011950.1 glutamate receptor-interacting protein 1 isoform X21

UniProtKB/TrEMBL

Q5DTG7

Conserved Domains (1) summary

cd00992
Location:153 → 236

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514242.5 → XP_006514305.1 glutamate receptor-interacting protein 1 isoform X16

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:126 → 209

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514235.4 → XP_006514298.1 glutamate receptor-interacting protein 1 isoform X5

UniProtKB/TrEMBL

A0A8I4SX76

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156054.1 → XP_036011947.1 glutamate receptor-interacting protein 1 isoform X17

UniProtKB/TrEMBL

D3YWY4

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514239.4 → XP_006514302.1 glutamate receptor-interacting protein 1 isoform X11

UniProtKB/TrEMBL

A0A8I4SX76

Conserved Domains (1) summary

cd00992
Location:151 → 234

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156058.1 → XP_036011951.1 glutamate receptor-interacting protein 1 isoform X22

UniProtKB/TrEMBL

D3YWY4

Conserved Domains (1) summary

cd00992
Location:151 → 234

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156049.1 → XP_036011942.1 glutamate receptor-interacting protein 1 isoform X6

UniProtKB/TrEMBL

A0A8I4SX76

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156055.1 → XP_036011948.1 glutamate receptor-interacting protein 1 isoform X19

UniProtKB/TrEMBL

A0A8I4SX76

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156050.1 → XP_036011943.1 glutamate receptor-interacting protein 1 isoform X7

UniProtKB/TrEMBL

A0A8I4SX76

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030245328.2 → XP_030101188.1 glutamate receptor-interacting protein 1 isoform X18

UniProtKB/TrEMBL

D3YWY4

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156056.1 → XP_036011949.1 glutamate receptor-interacting protein 1 isoform X20

UniProtKB/TrEMBL

A0A8I4SX76

Conserved Domains (1) summary

cd00992
Location:178 → 261

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156053.1 → XP_036011946.1 glutamate receptor-interacting protein 1 isoform X15

UniProtKB/TrEMBL

A0A8I4SX76

Related

ENSMUSP00001091665.1, ENSMUST00020183804.1

Conserved Domains (1) summary

cd00992
Location:151 → 234

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514231.4 → XP_006514294.1 glutamate receptor-interacting protein 1 isoform X1

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514233.4 → XP_006514296.1 glutamate receptor-interacting protein 1 isoform X2

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030245326.2 → XP_030101186.1 glutamate receptor-interacting protein 1 isoform X3

UniProtKB/TrEMBL

D3Z6T4

Related

ENSMUSP00000122323.2, ENSMUST00000144959.8

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156051.1 → XP_036011944.1 glutamate receptor-interacting protein 1 isoform X12

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514236.4 → XP_006514299.1 glutamate receptor-interacting protein 1 isoform X8

UniProtKB/TrEMBL

D3YWY4

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030245327.2 → XP_030101187.1 glutamate receptor-interacting protein 1 isoform X13

UniProtKB/TrEMBL

Q6NWW3

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514234.4 → XP_006514297.1 glutamate receptor-interacting protein 1 isoform X4

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:182 → 265

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_006514237.4 → XP_006514300.1 glutamate receptor-interacting protein 1 isoform X9

UniProtKB/TrEMBL

D3YWY4

Related

ENSMUSP00000118397.2, ENSMUST00000148954.8

Conserved Domains (1) summary

cd00992
Location:209 → 292

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156060.1 → XP_036011953.1 glutamate receptor-interacting protein 1 isoform X24

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:96 → 179

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_036156061.1 → XP_036011954.1 glutamate receptor-interacting protein 1 isoform X24

UniProtKB/TrEMBL

D3Z6T4

Conserved Domains (1) summary

cd00992
Location:96 → 179

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_030245329.2 → XP_030101189.1 glutamate receptor-interacting protein 1 isoform X25

UniProtKB/TrEMBL

Q6X4T6

Related

ENSMUSP00000123288.2, ENSMUST00000130387.8

Conserved Domains (1) summary

cd00992
Location:255 → 336

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...