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    Efcab12 EF-hand calcium binding domain 12 [ Mus musculus (house mouse) ]

    Gene ID: 212516, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Efcab12provided by MGI
    Official Full Name
    EF-hand calcium binding domain 12provided by MGI
    Primary source
    MGI:MGI:2681834
    See related
    Ensembl:ENSMUSG00000030321 AllianceGenome:MGI:2681834
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Is expressed in 4th ventricle lateral recess; choroid plexus; lateral ventricle choroid plexus; and olfactory epithelium. Orthologous to human EFCAB12 (EF-hand calcium binding domain 12). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 8.5), cortex adult (RPKM 1.7) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Efcab12 in Genome Data Viewer
    Location:
    6 E3; 6 53.72 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (115787695..115815177, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (115810729..115838577, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene microRNA 7660 Neighboring gene cullin associated and neddylation dissociated 2 (putative) Neighboring gene STARR-positive B cell enhancer ABC_E4857 Neighboring gene small nucleolar RNA, H/ACA box 7A Neighboring gene ribosomal protein L32 Neighboring gene STARR-positive B cell enhancer ABC_E2201 Neighboring gene STARR-positive B cell enhancer ABC_E11332 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:115803828-115803937 Neighboring gene methyl-CpG binding domain protein 4 Neighboring gene intraflagellar transport 122 Neighboring gene rhodopsin Neighboring gene rhodopsin enhancer region

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC69711

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    EF-hand calcium-binding domain-containing protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110506.2 → NP_001103976.1  EF-hand calcium-binding domain-containing protein 12 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC109169
      Consensus CDS
      CCDS71816.1
      UniProtKB/TrEMBL
      V9GXH0
      Related
      ENSMUSP00000139144.2, ENSMUST00000184428.6

    2. NM_001411524.1 → NP_001398453.1  EF-hand calcium-binding domain-containing protein 12 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC109169

    3. NM_001411533.1 → NP_001398462.1  EF-hand calcium-binding domain-containing protein 12 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC109169

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      115787695..115815177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198603.1: Suppressed sequence

      Description
      NM_198603.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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