U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    WNK2 WNK lysine deficient protein kinase 2 [ Homo sapiens (human) ]

    Gene ID: 65268, updated on 12-Nov-2024

    Summary

    Official Symbol
    WNK2provided by HGNC
    Official Full Name
    WNK lysine deficient protein kinase 2provided by HGNC
    Primary source
    HGNC:HGNC:14542
    See related
    Ensembl:ENSG00000165238 MIM:606249; AllianceGenome:HGNC:14542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRKWNK2; NY-CO-43; SDCCAG43; P/OKcl.13
    Summary
    The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
    Expression
    Broad expression in heart (RPKM 6.5), colon (RPKM 6.3) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See WNK2 in Genome Data Viewer
    Location:
    9q22.31
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (93184139..93320569)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (105350754..105487952)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (95946421..96082851)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902212 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28617 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20040 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20041 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:95897247-95897843 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:95905234-95906106 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:95906107-95906979 Neighboring gene Sharpr-MPRA regulatory region 13679 Neighboring gene ninjurin 1 Neighboring gene uncharacterized LOC124902213 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:95913665-95914165 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28619 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28620 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20043 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:95935533-95936106 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:95948459-95949424 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:95951526-95952459 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:95955296-95955514 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:95964080-95965013 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96000334-96000834 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96007029-96007528 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:96025151-96025819 Neighboring gene uncharacterized LOC124902214 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:96050932-96051728 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96061034-96061534 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96063483-96064395 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96068651-96069555 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96088631-96089132 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:96089133-96089632 Neighboring gene family with sequence similarity 120A2, pseudogene Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:96109682-96110628 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr9:96112805-96113334 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:96114925-96115454 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:96115455-96115984 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_109877 Neighboring gene RNA, U6 small nuclear 829, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1760

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein kinase WNK2
    Names
    antigen NY-CO-43
    mitogen-activated protein kinase kinase kinase
    protein kinase lysine-deficient 2
    protein kinase with no lysine 2
    serologically defined colon cancer antigen 43
    NP_001269323.1
    NP_006639.3
    XP_005252194.1
    XP_005252197.1
    XP_005252201.1
    XP_016870534.1
    XP_016870536.1
    XP_016870537.1
    XP_016870538.1
    XP_016870539.1
    XP_016870540.1
    XP_016870541.1
    XP_016870542.1
    XP_016870543.1
    XP_016870544.1
    XP_047279697.1
    XP_047279698.1
    XP_047279699.1
    XP_047279700.1
    XP_047279701.1
    XP_047279702.1
    XP_047279703.1
    XP_047279704.1
    XP_047279705.1
    XP_047279706.1
    XP_047279707.1
    XP_047279708.1
    XP_047279709.1
    XP_047279710.1
    XP_047279712.1
    XP_047279713.1
    XP_047279714.1
    XP_047279715.1
    XP_047279716.1
    XP_047279717.1
    XP_047279718.1
    XP_047279719.1
    XP_047279720.1
    XP_047279721.1
    XP_047279723.1
    XP_047279724.1
    XP_047279725.1
    XP_047279726.1
    XP_047279727.1
    XP_047279728.1
    XP_047279729.1
    XP_047279730.1
    XP_047279731.1
    XP_047279732.1
    XP_047279734.1
    XP_047279735.1
    XP_054219548.1
    XP_054219549.1
    XP_054219550.1
    XP_054219551.1
    XP_054219552.1
    XP_054219553.1
    XP_054219554.1
    XP_054219555.1
    XP_054219556.1
    XP_054219557.1
    XP_054219558.1
    XP_054219559.1
    XP_054219560.1
    XP_054219561.1
    XP_054219562.1
    XP_054219563.1
    XP_054219564.1
    XP_054219565.1
    XP_054219566.1
    XP_054219567.1
    XP_054219568.1
    XP_054219569.1
    XP_054219570.1
    XP_054219571.1
    XP_054219572.1
    XP_054219573.1
    XP_054219574.1
    XP_054219575.1
    XP_054219576.1
    XP_054219577.1
    XP_054219578.1
    XP_054219579.1
    XP_054219580.1
    XP_054219581.1
    XP_054219582.1
    XP_054219583.1
    XP_054219584.1
    XP_054219585.1
    XP_054219586.1
    XP_054219587.1
    XP_054219588.1
    XP_054219589.1
    XP_054219590.1
    XP_054219591.1
    XP_054219592.1
    XP_054219593.1
    XP_054219594.1
    XP_054219595.1
    XP_054219596.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282394.3NP_001269323.1  serine/threonine-protein kinase WNK2 isoform 1

      See identical proteins and their annotated locations for NP_001269323.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AL354991, AL390760, AL583839
      Consensus CDS
      CCDS75858.1
      UniProtKB/Swiss-Prot
      Q5VWF1, Q5VWF2, Q8IY36, Q9C0A3, Q9H3P4, Q9Y3S1
      UniProtKB/TrEMBL
      H0Y7T5
      Related
      ENSP00000297954.4, ENST00000297954.9
      Conserved Domains (3) summary
      smart00220
      Location:200453
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14032
      Location:193458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474511
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
    2. NM_006648.4NP_006639.3  serine/threonine-protein kinase WNK2 isoform 2

      See identical proteins and their annotated locations for NP_006639.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the coding region and uses an alternate splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AL354991, AL390760, AL583839
      UniProtKB/TrEMBL
      E9PCD1, F8W9F9, H0Y7T5
      Related
      ENSP00000411181.4, ENST00000427277.7
      Conserved Domains (3) summary
      smart00220
      Location:200453
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14032
      Location:193458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474511
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      93184139..93320569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047423745.1XP_047279701.1  serine/threonine-protein kinase WNK2 isoform X16

    2. XM_047423751.1XP_047279707.1  serine/threonine-protein kinase WNK2 isoform X22

    3. XM_047423761.1XP_047279717.1  serine/threonine-protein kinase WNK2 isoform X33

    4. XM_047423767.1XP_047279723.1  serine/threonine-protein kinase WNK2 isoform X38

    5. XM_047423754.1XP_047279710.1  serine/threonine-protein kinase WNK2 isoform X27

    6. XM_047423741.1XP_047279697.1  serine/threonine-protein kinase WNK2 isoform X8

    7. XM_047423747.1XP_047279703.1  serine/threonine-protein kinase WNK2 isoform X18

    8. XM_047423752.1XP_047279708.1  serine/threonine-protein kinase WNK2 isoform X23

    9. XM_047423762.1XP_047279718.1  serine/threonine-protein kinase WNK2 isoform X34

    10. XM_047423768.1XP_047279724.1  serine/threonine-protein kinase WNK2 isoform X39

    11. XM_047423753.1XP_047279709.1  serine/threonine-protein kinase WNK2 isoform X24

    12. XM_047423756.1XP_047279712.1  serine/threonine-protein kinase WNK2 isoform X28

    13. XM_047423770.1XP_047279726.1  serine/threonine-protein kinase WNK2 isoform X41

    14. XM_047423771.1XP_047279727.1  serine/threonine-protein kinase WNK2 isoform X42

    15. XM_005252137.4XP_005252194.1  serine/threonine-protein kinase WNK2 isoform X1

      UniProtKB/TrEMBL
      H0Y7T5
      Conserved Domains (3) summary
      smart00220
      Location:200453
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14032
      Location:193458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474511
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
    16. XM_005252140.3XP_005252197.1  serine/threonine-protein kinase WNK2 isoform X7

      UniProtKB/TrEMBL
      H0Y7T5
      Related
      ENSP00000415038.2, ENST00000432730.6
      Conserved Domains (3) summary
      smart00220
      Location:200453
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14032
      Location:193458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474511
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
    17. XM_017015049.2XP_016870538.1  serine/threonine-protein kinase WNK2 isoform X5

      UniProtKB/TrEMBL
      H0Y7T5
    18. XM_047423742.1XP_047279698.1  serine/threonine-protein kinase WNK2 isoform X10

    19. XM_047423749.1XP_047279705.1  serine/threonine-protein kinase WNK2 isoform X20

    20. XM_017015054.2XP_016870543.1  serine/threonine-protein kinase WNK2 isoform X25

      UniProtKB/TrEMBL
      H0Y7T5
    21. XM_047423757.1XP_047279713.1  serine/threonine-protein kinase WNK2 isoform X29

    22. XM_047423764.1XP_047279720.1  serine/threonine-protein kinase WNK2 isoform X36

    23. XM_017015047.2XP_016870536.1  serine/threonine-protein kinase WNK2 isoform X3

      UniProtKB/TrEMBL
      H0Y7T5
    24. XM_017015052.2XP_016870541.1  serine/threonine-protein kinase WNK2 isoform X12

      UniProtKB/TrEMBL
      H0Y7T5
    25. XM_047423744.1XP_047279700.1  serine/threonine-protein kinase WNK2 isoform X14

    26. XM_017015045.2XP_016870534.1  serine/threonine-protein kinase WNK2 isoform X2

      UniProtKB/TrEMBL
      H0Y7T5
    27. XM_017015050.2XP_016870539.1  serine/threonine-protein kinase WNK2 isoform X6

      UniProtKB/TrEMBL
      H0Y7T5
    28. XM_047423743.1XP_047279699.1  serine/threonine-protein kinase WNK2 isoform X11

    29. XM_047423750.1XP_047279706.1  serine/threonine-protein kinase WNK2 isoform X21

    30. XM_017015055.2XP_016870544.1  serine/threonine-protein kinase WNK2 isoform X26

      UniProtKB/TrEMBL
      H0Y7T5
    31. XM_047423758.1XP_047279714.1  serine/threonine-protein kinase WNK2 isoform X30

    32. XM_047423765.1XP_047279721.1  serine/threonine-protein kinase WNK2 isoform X37

    33. XM_017015048.2XP_016870537.1  serine/threonine-protein kinase WNK2 isoform X4

      UniProtKB/TrEMBL
      H0Y7T5
    34. XM_017015053.2XP_016870542.1  serine/threonine-protein kinase WNK2 isoform X13

      UniProtKB/TrEMBL
      H0Y7T5
    35. XM_017015051.2XP_016870540.1  serine/threonine-protein kinase WNK2 isoform X9

      UniProtKB/TrEMBL
      H0Y7T5
    36. XM_047423748.1XP_047279704.1  serine/threonine-protein kinase WNK2 isoform X19

    37. XM_005252144.3XP_005252201.1  serine/threonine-protein kinase WNK2 isoform X15

      UniProtKB/TrEMBL
      H0Y7T5
      Conserved Domains (3) summary
      smart00220
      Location:200453
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14032
      Location:193458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474511
      OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
    38. XM_047423759.1XP_047279715.1  serine/threonine-protein kinase WNK2 isoform X31

    39. XM_047423769.1XP_047279725.1  serine/threonine-protein kinase WNK2 isoform X40

    40. XM_047423763.1XP_047279719.1  serine/threonine-protein kinase WNK2 isoform X35

    41. XM_047423746.1XP_047279702.1  serine/threonine-protein kinase WNK2 isoform X17

    42. XM_047423760.1XP_047279716.1  serine/threonine-protein kinase WNK2 isoform X32

    43. XM_047423773.1XP_047279729.1  serine/threonine-protein kinase WNK2 isoform X44

    44. XM_047423778.1XP_047279734.1  serine/threonine-protein kinase WNK2 isoform X48

    45. XM_047423774.1XP_047279730.1  serine/threonine-protein kinase WNK2 isoform X45

    46. XM_047423775.1XP_047279731.1  serine/threonine-protein kinase WNK2 isoform X46

      Related
      ENSP00000414622.1, ENST00000411624.5
    47. XM_047423772.1XP_047279728.1  serine/threonine-protein kinase WNK2 isoform X43

    48. XM_047423776.1XP_047279732.1  serine/threonine-protein kinase WNK2 isoform X47

    49. XM_047423779.1XP_047279735.1  serine/threonine-protein kinase WNK2 isoform X49

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      105350754..105487952
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054363588.1XP_054219563.1  serine/threonine-protein kinase WNK2 isoform X16

    2. XM_054363594.1XP_054219569.1  serine/threonine-protein kinase WNK2 isoform X22

    3. XM_054363605.1XP_054219580.1  serine/threonine-protein kinase WNK2 isoform X33

    4. XM_054363610.1XP_054219585.1  serine/threonine-protein kinase WNK2 isoform X38

    5. XM_054363599.1XP_054219574.1  serine/threonine-protein kinase WNK2 isoform X27

    6. XM_054363580.1XP_054219555.1  serine/threonine-protein kinase WNK2 isoform X8

    7. XM_054363590.1XP_054219565.1  serine/threonine-protein kinase WNK2 isoform X18

    8. XM_054363595.1XP_054219570.1  serine/threonine-protein kinase WNK2 isoform X23

    9. XM_054363606.1XP_054219581.1  serine/threonine-protein kinase WNK2 isoform X34

    10. XM_054363611.1XP_054219586.1  serine/threonine-protein kinase WNK2 isoform X39

    11. XM_054363596.1XP_054219571.1  serine/threonine-protein kinase WNK2 isoform X24

    12. XM_054363600.1XP_054219575.1  serine/threonine-protein kinase WNK2 isoform X28

    13. XM_054363613.1XP_054219588.1  serine/threonine-protein kinase WNK2 isoform X41

    14. XM_054363614.1XP_054219589.1  serine/threonine-protein kinase WNK2 isoform X42

    15. XM_054363573.1XP_054219548.1  serine/threonine-protein kinase WNK2 isoform X1

    16. XM_054363579.1XP_054219554.1  serine/threonine-protein kinase WNK2 isoform X7

    17. XM_054363577.1XP_054219552.1  serine/threonine-protein kinase WNK2 isoform X5

    18. XM_054363582.1XP_054219557.1  serine/threonine-protein kinase WNK2 isoform X10

    19. XM_054363592.1XP_054219567.1  serine/threonine-protein kinase WNK2 isoform X20

    20. XM_054363597.1XP_054219572.1  serine/threonine-protein kinase WNK2 isoform X25

    21. XM_054363601.1XP_054219576.1  serine/threonine-protein kinase WNK2 isoform X29

    22. XM_054363608.1XP_054219583.1  serine/threonine-protein kinase WNK2 isoform X36

    23. XM_054363575.1XP_054219550.1  serine/threonine-protein kinase WNK2 isoform X3

    24. XM_054363584.1XP_054219559.1  serine/threonine-protein kinase WNK2 isoform X12

    25. XM_054363586.1XP_054219561.1  serine/threonine-protein kinase WNK2 isoform X14

    26. XM_054363574.1XP_054219549.1  serine/threonine-protein kinase WNK2 isoform X2

    27. XM_054363578.1XP_054219553.1  serine/threonine-protein kinase WNK2 isoform X6

    28. XM_054363583.1XP_054219558.1  serine/threonine-protein kinase WNK2 isoform X11

    29. XM_054363593.1XP_054219568.1  serine/threonine-protein kinase WNK2 isoform X21

    30. XM_054363598.1XP_054219573.1  serine/threonine-protein kinase WNK2 isoform X26

    31. XM_054363602.1XP_054219577.1  serine/threonine-protein kinase WNK2 isoform X30

    32. XM_054363609.1XP_054219584.1  serine/threonine-protein kinase WNK2 isoform X37

    33. XM_054363576.1XP_054219551.1  serine/threonine-protein kinase WNK2 isoform X4

    34. XM_054363585.1XP_054219560.1  serine/threonine-protein kinase WNK2 isoform X13

    35. XM_054363581.1XP_054219556.1  serine/threonine-protein kinase WNK2 isoform X9

    36. XM_054363591.1XP_054219566.1  serine/threonine-protein kinase WNK2 isoform X19

    37. XM_054363587.1XP_054219562.1  serine/threonine-protein kinase WNK2 isoform X15

    38. XM_054363603.1XP_054219578.1  serine/threonine-protein kinase WNK2 isoform X31

    39. XM_054363612.1XP_054219587.1  serine/threonine-protein kinase WNK2 isoform X40

    40. XM_054363607.1XP_054219582.1  serine/threonine-protein kinase WNK2 isoform X35

    41. XM_054363589.1XP_054219564.1  serine/threonine-protein kinase WNK2 isoform X17

    42. XM_054363604.1XP_054219579.1  serine/threonine-protein kinase WNK2 isoform X32

    43. XM_054363616.1XP_054219591.1  serine/threonine-protein kinase WNK2 isoform X44

    44. XM_054363620.1XP_054219595.1  serine/threonine-protein kinase WNK2 isoform X48

    45. XM_054363617.1XP_054219592.1  serine/threonine-protein kinase WNK2 isoform X45

    46. XM_054363618.1XP_054219593.1  serine/threonine-protein kinase WNK2 isoform X46

    47. XM_054363615.1XP_054219590.1  serine/threonine-protein kinase WNK2 isoform X43

    48. XM_054363619.1XP_054219594.1  serine/threonine-protein kinase WNK2 isoform X47

    49. XM_054363621.1XP_054219596.1  serine/threonine-protein kinase WNK2 isoform X49