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    FHIP2A FHF complex subunit HOOK interacting protein 2A [ Homo sapiens (human) ]

    Gene ID: 57700, updated on 6-Oct-2024

    Summary

    Official Symbol
    FHIP2Aprovided by HGNC
    Official Full Name
    FHF complex subunit HOOK interacting protein 2Aprovided by HGNC
    Primary source
    HGNC:HGNC:29320
    See related
    Ensembl:ENSG00000151553 MIM:617312; AllianceGenome:HGNC:29320
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM160B1; KIAA1600; bA106M7.3
    Expression
    Ubiquitous expression in bone marrow (RPKM 14.0), endometrium (RPKM 9.6) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See FHIP2A in Genome Data Viewer
    Location:
    10q25.3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (114821780..114899832)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (115715884..115793964)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (116581539..116659591)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene actin binding LIM protein 1 Neighboring gene uncharacterized LOC101927692 Neighboring gene translation initiation factor IF-2-like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4089 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4090 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4091 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2846 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:116581943-116582443 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2847 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4092 Neighboring gene TATA-box binding protein associated factor 9b pseudogene 2 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:116640543-116641171 Neighboring gene Sharpr-MPRA regulatory region 3306 Neighboring gene ribosomal protein L15 pseudogene 13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4093 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2849 Neighboring gene MPRA-validated peak1102 silencer Neighboring gene RNA, U6 small nuclear 1121, pseudogene Neighboring gene TruB pseudouridine synthase family member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1600, DKFZp686D10123

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    FHF complex subunit HOOK interacting protein 2A
    Names
    family with sequence similarity 160 member B1
    protein FAM160B1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135051.2NP_001128523.1  FHF complex subunit HOOK interacting protein 2A isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
      Source sequence(s)
      AL137025, BC037207
      Consensus CDS
      CCDS44480.1
      UniProtKB/TrEMBL
      A0AA34QVS8
      Related
      ENSP00000358253.3, ENST00000369250.7
      Conserved Domains (1) summary
      pfam10257
      Location:78495
      RAI16-like; Retinoic acid induced 16-like protein
    2. NM_020940.4NP_065991.3  FHF complex subunit HOOK interacting protein 2A isoform a

      See identical proteins and their annotated locations for NP_065991.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AB046820, AI521900, BC037207, CR933692
      Consensus CDS
      CCDS31290.1
      UniProtKB/Swiss-Prot
      Q5H9P7, Q5W0V2, Q5W0V3, Q8IY76, Q9HCH2
      UniProtKB/TrEMBL
      A0AA34QVS8
      Related
      ENSP00000358251.4, ENST00000369248.9
      Conserved Domains (1) summary
      pfam10257
      Location:78495
      RAI16-like; Retinoic acid induced 16-like protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      114821780..114899832
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      115715884..115793964
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)