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    GUT1 glycerol kinase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856353, updated on 17-May-2024

    Summary

    Gene symbol
    GUT1
    Gene description
    glycerol kinase
    Primary source
    FungiDB:YHL032C
    Locus tag
    YHL032C
    See related
    SGD:S000001024; AllianceGenome:SGD:S000001024; VEuPathDB:YHL032C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables glycerol kinase activity. Involved in glycerol metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase) and GK2 (glycerol kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See GUT1 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (36379..38508, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Sbp1p Neighboring gene ribosomal 60S subunit protein L8A Neighboring gene Gos1p Neighboring gene Ecm29p

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycerol kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycerol kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in glycerol-3-phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycerol-3-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in triglyceride metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    glycerol kinase
    NP_011831.1
    • Glycerol kinase; converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      36379..38508 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179112.1NP_011831.1  TPA: glycerol kinase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011831.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKT6, P32190
      UniProtKB/TrEMBL
      A0A8H4C1X1, A6ZSL8, B3LS87, C7GIQ4
      Conserved Domains (1) summary
      cl17037
      Location:46685
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily