Map2 microtubule-associated protein 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Map2provided by MGI
Official Full Name: microtubule-associated protein 2provided by MGI
Primary source: MGI:MGI:97175
See related: Ensembl:ENSMUSG00000015222 AllianceGenome:MGI:97175
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
Summary: Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; negative regulation of axon extension; and regulation of protein localization. Acts upstream of or within establishment of cell polarity; microtubule bundle formation; and neuron projection development. Located in several cellular components, including axon; dendrite; and proximal neuron projection. Is active in cell body. Is expressed in several structures, including back skin; central nervous system; maxillary process; peripheral nervous system ganglion; and retina. Orthologous to human MAP2 (microtubule associated protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in CNS E18 (RPKM 41.7), frontal lobe adult (RPKM 39.0) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 C3; 1 33.49 cM

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (66214337..66481742)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (66175202..66442583)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MAP2 is differentially phosphorylated in schizophrenia, altering its function.
Title: MAP2 is differentially phosphorylated in schizophrenia, altering its function.
Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.
Title: Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.
MAP2c levels in different brain regions of aging mice were positively correlated with neuropsin expression.
Title: Neuropsin Expression Correlates with Dendritic Marker MAP2c Level in Different Brain Regions of Aging Mice.
Accumulation of intraneuronal beta-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
Title: Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
results demonstrate the structural and functional determinant underlying the v-KIND-MAP2 interaction that controls dendrite arborization patterns
Title: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain.
Increased MAP2 expression in malignant melanoma cells significantly inhibits tumor cell growth and neoplasm invasiveness, and induces apoptosis and cell cycle arrest.
Title: Increased expression of MAP2 inhibits melanoma cell proliferation, invasion and tumor growth in vitro and in vivo.
Data show that inhibition of ZNF238 (RP58) expression in mouse GNPs decreases the expression of the neuronal differentiation markers MAP2 and NeuN and downregulates the expression of the cell cycle arrest protein p27, a regulator of GNP differentiation.
Title: ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth.
AKAP150 and Mtap2 put TREK channels at the center of a complex protein network that finely tunes channel trafficking, addressing, and regulation.
Title: Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.
v-KIND mediates a signaling pathway that links Ras and MAP2 to control dendrite growth
Title: Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2.
JNK1 phosphorylation of MAP2 plays an important role in defining dendritic architecture in the brain.
Title: Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector.

Submit: New GeneRIF Correction See all GeneRIFs (18)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Chemically induced (ENU) (1)
Endonuclease-mediated (4)
Targeted (3) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

35.MMHAP90FRD11.seq (e-PCR)
- UniSTS:124163

Mtap2 (e-PCR), detects polymorphism
- UniSTS:531079

Mtap2 (e-PCR), detects polymorphism
- UniSTS:502667

Mtap2 (e-PCR), detects polymorphism
- UniSTS:497296

Mtap2 (e-PCR), detects polymorphism
- UniSTS:275868

29.MMHAP15FLB5.seq (e-PCR)
- UniSTS:123848

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables actin binding	ISO Inferred from Sequence Orthology more info
enables calmodulin binding	IEA Inferred from Electronic Annotation more info
enables cytoskeletal regulatory protein binding	TAS Traceable Author Statement more info	PubMed
enables dystroglycan binding	ISO Inferred from Sequence Orthology more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IDA Inferred from Direct Assay more info	PubMed
enables microtubule binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axonogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within axonogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within dendrite development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within establishment of cell polarity	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within microtubule bundle formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule cytoskeleton organization	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of axon extension	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of axon extension	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of microtubule depolymerization	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of microtubule polymerization	ISO Inferred from Sequence Orthology more info
involved_in neuron projection development	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of anterograde dense core granule transport	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of anterograde synaptic vesicle transport	ISO Inferred from Sequence Orthology more info
involved_in regulation of organelle transport along microtubule	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of protein localization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in CA3 pyramidal cell dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in actin cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in apical dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in apical distal dendrite	ISO Inferred from Sequence Orthology more info
located_in axon hillock	IDA Inferred from Direct Assay more info	PubMed
located_in axon hillock	ISO Inferred from Sequence Orthology more info
located_in axon initial segment	IDA Inferred from Direct Assay more info	PubMed
located_in axon initial segment	ISO Inferred from Sequence Orthology more info
located_in basal dendrite	ISO Inferred from Sequence Orthology more info
is_active_in cell body	IDA Inferred from Direct Assay more info	PubMed
located_in cell body	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	ISO Inferred from Sequence Orthology more info	PubMed
located_in dendrite cytoplasm	ISO Inferred from Sequence Orthology more info
located_in dendritic branch	ISO Inferred from Sequence Orthology more info
located_in dendritic filopodium	ISO Inferred from Sequence Orthology more info
located_in dendritic growth cone	ISO Inferred from Sequence Orthology more info
located_in dendritic shaft	IDA Inferred from Direct Assay more info	PubMed
located_in dendritic shaft	ISO Inferred from Sequence Orthology more info
located_in distal dendrite	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in intracellular anatomical structure	IDA Inferred from Direct Assay more info	PubMed
located_in microtubule	IEA Inferred from Electronic Annotation more info
part_of microtubule associated complex	TAS Traceable Author Statement more info	PubMed
located_in microtubule cytoskeleton	ISO Inferred from Sequence Orthology more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in neuron projection	IDA Inferred from Direct Assay more info	PubMed
located_in neuron projection	ISO Inferred from Sequence Orthology more info	PubMed
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
located_in neuronal cell body	ISO Inferred from Sequence Orthology more info
located_in nuclear periphery	IDA Inferred from Direct Assay more info	PubMed
is_active_in postsynapse	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	IDA Inferred from Direct Assay more info	PubMed
located_in primary dendrite	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
located_in proximal dendrite	ISO Inferred from Sequence Orthology more info
located_in proximal neuron projection	IDA Inferred from Direct Assay more info	PubMed
located_in proximal neuron projection	ISO Inferred from Sequence Orthology more info
located_in ruffle membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: microtubule-associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039934.2 → NP_001035023.1 microtubule-associated protein 2 isoform 1

See identical proteins and their annotated locations for NP_001035023.1

Status: VALIDATED

Source sequence(s)

AC091465, AC114403

Consensus CDS

CCDS15020.1

UniProtKB/TrEMBL

B2KGT5, Q3TLQ0, Q80X35

Related

ENSMUSP00000109650.2, ENSMUST00000114017.8

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
NM_001310634.2 → NP_001297563.1 microtubule-associated protein 2 isoform 3

See identical proteins and their annotated locations for NP_001297563.1

Status: VALIDATED

Source sequence(s)

AC091465

Consensus CDS

CCDS83550.1

UniProtKB/Swiss-Prot

E9QLE1, P20357

UniProtKB/TrEMBL

A0A668KLC6

Related

ENSMUSP00000109646.2, ENSMUST00000114013.8

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
NM_001431748.1 → NP_001418677.1 microtubule-associated protein 2 isoform 3

Status: VALIDATED

Source sequence(s)

AC091465, AC114403

UniProtKB/Swiss-Prot

E9QLE1, P20357
NM_008632.3 → NP_032658.2 microtubule-associated protein 2 isoform 2

See identical proteins and their annotated locations for NP_032658.2

Status: VALIDATED

Source sequence(s)

AC091465, AC114403

Consensus CDS

CCDS35602.1

UniProtKB/TrEMBL

B2KGT5, Q80X35, Q80ZL4

Related

ENSMUSP00000109648.2, ENSMUST00000114015.8

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000067.7 Reference GRCm39 C57BL/6J

Range

66214337..66481742

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006495762.5 → XP_006495825.1 microtubule-associated protein 2 isoform X17

See identical proteins and their annotated locations for XP_006495825.1

UniProtKB/TrEMBL

B2KGT5, Q80X35, Q80ZL4

Related

ENSMUSP00000024639.6, ENSMUST00000024639.12

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_036162607.1 → XP_036018500.1 microtubule-associated protein 2 isoform X19

UniProtKB/TrEMBL

A0A668KLC6

Related

ENSMUSP00000159224.2, ENSMUST00000239213.2

Conserved Domains (2) summary

pfam08377
Location:458 → 1592

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1806 → 1837

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495746.4 → XP_006495809.1 microtubule-associated protein 2 isoform X1

See identical proteins and their annotated locations for XP_006495809.1

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_006495754.4 → XP_006495817.1 microtubule-associated protein 2 isoform X7

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_006495751.4 → XP_006495814.1 microtubule-associated protein 2 isoform X3

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1692 → 1721

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_006495756.4 → XP_006495819.1 microtubule-associated protein 2 isoform X9

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1692 → 1721

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_006495750.4 → XP_006495813.1 microtubule-associated protein 2 isoform X2

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1692 → 1721

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1509

MAP2_projctn; MAP2/Tau projection domain
XM_017319166.3 → XP_017174655.1 microtubule-associated protein 2 isoform X8

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1692 → 1721

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1509

MAP2_projctn; MAP2/Tau projection domain
XM_006495752.4 → XP_006495815.1 microtubule-associated protein 2 isoform X4

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1691 → 1720

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1509

MAP2_projctn; MAP2/Tau projection domain
XM_017319175.3 → XP_017174664.1 microtubule-associated protein 2 isoform X10

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1691 → 1720

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1509

MAP2_projctn; MAP2/Tau projection domain
XM_006495753.4 → XP_006495816.1 microtubule-associated protein 2 isoform X5

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam08377
Location:372 → 1506

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1689 → 1719

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495757.4 → XP_006495820.1 microtubule-associated protein 2 isoform X11

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1689 → 1718

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:372 → 1506

MAP2_projctn; MAP2/Tau projection domain
XM_036162582.1 → XP_036018475.1 microtubule-associated protein 2 isoform X13

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam08377
Location:372 → 1506

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1719 → 1750

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_036162575.1 → XP_036018468.1 microtubule-associated protein 2 isoform X6

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam08377
Location:372 → 1505

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1688 → 1718

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_036162581.1 → XP_036018474.1 microtubule-associated protein 2 isoform X12

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam08377
Location:372 → 1505

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1719 → 1750

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495759.5 → XP_006495822.1 microtubule-associated protein 2 isoform X15

See identical proteins and their annotated locations for XP_006495822.1

UniProtKB/TrEMBL

B2KGT5, Q3TLQ0, Q80X35

Related

ENSMUSP00000109651.4, ENSMUST00000114018.10

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495761.5 → XP_006495824.1 microtubule-associated protein 2 isoform X16

UniProtKB/TrEMBL

B2KGT5, Q80X35

Conserved Domains (1) summary

pfam00418
Location:331 → 360

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_036162601.1 → XP_036018494.1 microtubule-associated protein 2 isoform X18

UniProtKB/TrEMBL

B2KGT5, Q80X35

Conserved Domains (1) summary

pfam00418
Location:362 → 393

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_011238448.3 → XP_011236750.1 microtubule-associated protein 2 isoform X1

See identical proteins and their annotated locations for XP_011236750.1

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_030251990.2 → XP_030107850.1 microtubule-associated protein 2 isoform X16

UniProtKB/TrEMBL

B2KGT5, Q80X35

Conserved Domains (1) summary

pfam00418
Location:331 → 360

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_030251982.1 → XP_030107842.1 microtubule-associated protein 2 isoform X15

UniProtKB/TrEMBL

B2KGT5, Q3TLQ0, Q80X35

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495748.5 → XP_006495811.1 microtubule-associated protein 2 isoform X1

See identical proteins and their annotated locations for XP_006495811.1

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_006495749.5 → XP_006495812.1 microtubule-associated protein 2 isoform X1

See identical proteins and their annotated locations for XP_006495812.1

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_036162573.1 → XP_036018466.1 microtubule-associated protein 2 isoform X5

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam08377
Location:372 → 1506

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1689 → 1719

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_030251986.2 → XP_030107846.1 microtubule-associated protein 2 isoform X15

UniProtKB/TrEMBL

B2KGT5, Q3TLQ0, Q80X35

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_030251996.2 → XP_030107856.1 microtubule-associated protein 2 isoform X17

UniProtKB/TrEMBL

B2KGT5, Q80X35, Q80ZL4

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_030251993.2 → XP_030107853.1 microtubule-associated protein 2 isoform X16

UniProtKB/TrEMBL

B2KGT5, Q80X35

Conserved Domains (1) summary

pfam00418
Location:331 → 360

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495747.5 → XP_006495810.1 microtubule-associated protein 2 isoform X1

See identical proteins and their annotated locations for XP_006495810.1

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1693 → 1722

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_017319165.3 → XP_017174654.1 microtubule-associated protein 2 isoform X3

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1692 → 1721

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_017319169.3 → XP_017174658.1 microtubule-associated protein 2 isoform X9

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1692 → 1721

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:376 → 1510

MAP2_projctn; MAP2/Tau projection domain
XM_030251971.2 → XP_030107831.1 microtubule-associated protein 2 isoform X5

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam08377
Location:372 → 1506

MAP2_projctn; MAP2/Tau projection domain

pfam00418
Location:1689 → 1719

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495760.3 → XP_006495823.1 microtubule-associated protein 2 isoform X15

See identical proteins and their annotated locations for XP_006495823.1

UniProtKB/TrEMBL

B2KGT5, Q3TLQ0, Q80X35

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_017319194.3 → XP_017174683.1 microtubule-associated protein 2 isoform X17

UniProtKB/TrEMBL

B2KGT5, Q80X35, Q80ZL4

Conserved Domains (1) summary

pfam00418
Location:332 → 361

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_030251989.2 → XP_030107849.1 microtubule-associated protein 2 isoform X16

UniProtKB/TrEMBL

B2KGT5, Q80X35

Conserved Domains (1) summary

pfam00418
Location:331 → 360

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_036162604.1 → XP_036018497.1 microtubule-associated protein 2 isoform X18

UniProtKB/TrEMBL

B2KGT5, Q80X35

Conserved Domains (1) summary

pfam00418
Location:362 → 393

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
XM_006495758.5 → XP_006495821.1 microtubule-associated protein 2 isoform X14

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1535 → 1564

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:218 → 1352

MAP2_projctn; MAP2/Tau projection domain
XM_030251978.2 → XP_030107838.1 microtubule-associated protein 2 isoform X14

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1535 → 1564

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:218 → 1352

MAP2_projctn; MAP2/Tau projection domain
XM_030251976.2 → XP_030107836.1 microtubule-associated protein 2 isoform X14

UniProtKB/TrEMBL

A0A668KLC6

Conserved Domains (2) summary

pfam00418
Location:1535 → 1564

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

pfam08377
Location:218 → 1352

MAP2_projctn; MAP2/Tau projection domain