RPC37 DNA-directed RNA polymerase III subunit C37 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: RPC37
Official Full Name: DNA-directed RNA polymerase III subunit C37
Primary source: SGD:S000001733
Locus tag: YKR025W
See related: AllianceGenome:SGD:S000001733; FungiDB:YKR025W; VEuPathDB:YKR025W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Contributes to RNA polymerase III activity. Involved in tRNA transcription by RNA polymerase III. Part of RNA polymerase III complex. Orthologous to human POLR3E (RNA polymerase III subunit E). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome XI - NC_001143.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Date indicate that RNA Polymerase III (RNAP III) subunits C53, C37, and C11 are required for pre-termination complex (PTC) formation.
Title: Mechanism of Transcription Termination by RNA Polymerase III Utilizes a Non-template Strand Sequence-Specific Signal Element.
C53/C37 subcomplex additionally plays a role in formation of the initiation-ready open promoter complex
Title: The C53/C37 subcomplex of RNA polymerase III lies near the active site and participates in promoter opening.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to RNA polymerase III activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in tRNA transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA transcription by RNA polymerase III	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of DNA-directed RNA polymerase complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase III complex	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_012950.3

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The following sections contain reference sequences that belong to a specific genome build. Explain