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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856335, updated on 2-Nov-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000001042
    Locus tag
    YHL050C
    See related
    AllianceGenome:SGD:S000001042; FungiDB:YHL050C; VEuPathDB:YHL050C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable helicase activity. Predicted to be located in membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome and primary immunodeficiency disease. Orthologous to human DHX58 (DExH-box helicase 58); RIGI (RNA sensor RIG-I); and IFIH1 (interferon induced with helicase C domain 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    Location:
    chromosome: VIII
    Exon count:
    2
    Sequence:
    Chromosome: VIII; NC_001140.6 (445..3311, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_011813.1
    • hypothetical protein; potential Cdc28p substrate

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      445..3311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179130.1 → NP_011813.1  TPA: uncharacterized protein YHL050C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011813.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKS0, P38721
      Conserved Domains (3) summary
      COG0513
      Location:3 → 187
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      cl21455
      Location:6 → 164
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
      cl23921
      Location:494 → 547
      YccJ; YccJ-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38721.1

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