U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cotC spore coat protein (outer) [ Bacillus subtilis subsp. subtilis str. 168 ]

    Gene ID: 939543, updated on 12-Feb-2021

    Summary

    Go to the top of the page Help
    Gene symbol
    cotC
    Gene description
    spore coat protein (outer)
    Locus tag
    BSU_17700
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
    Lineage
    Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
    Old locus tag
    BSU17700
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000964.3 (1904995..1905195, complement)

    NC_000964.3Genomic Context describing neighboring genes Neighboring gene conserved exported protein Neighboring gene putative membrane protein of unknown function (phage origin) Neighboring gene component of the twin-arginine pre-protein translocation pathway Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000964.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The choice of the anchoring protein influences the interaction of recombinant Bacillus spores with the immune system. Piekarska A, et al. Acta Biochim Pol, 2017. PMID 28399189
    2. Direct and indirect control of late sporulation genes by GerR of Bacillus subtilis. Cangiano G, et al. J Bacteriol, 2010 Jul. PMID 20435725, Free PMC Article
    3. CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat. Isticato R, et al. J Bacteriol, 2008 Feb. PMID 18065538, Free PMC Article
    4. Localization of proteins to different layers and regions of Bacillus subtilis spore coats. Imamura D, et al. J Bacteriol, 2010 Jan. PMID 19933362, Free PMC Article
    5. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In this study, we compared four variants of B. subtilis spores presenting a fragment of a FliD protein from Clostridium difficile in fusion with CotB, CotC, CotG or CotZ spore coat proteins. We show that these spores promote their own phagocytosis and activate both, the J774 macrophages and JAWSII dendritic cells of murine cell lines.
      Title: The choice of the anchoring protein influences the interaction of recombinant Bacillus spores with the immune system.
    2. GerR's effect in regulating the expression of several late sporulation genes is seen that it is strongly positive on spoVIF, cotC, and cotG, weakly positive on cotB, and negative on cotU.
      Title: Direct and indirect control of late sporulation genes by GerR of Bacillus subtilis.
    3. CotA and CotC were more abundant at the mother cell distal pole of the forespore.
      Title: Localization of proteins to different layers and regions of Bacillus subtilis spore coats.
    4. Data show that CotC and CotU, are produced concurrently in the mother cell chamber of the sporulating cell and immediately assembled around the forming spore and interacted to form a coat component of 23 kDa.
      Title: CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat.
    Submit: New GeneRIF Correction

    General protein information

    Go to the top of the page Help
    Preferred Names
    spore coat protein (outer)
    NP_389653.2
    • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10788508, 11741866, 14762008, 18065538, 2821284, 19933362, 20023017; Product type s: structure

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000964.3 Reference assembly

      Range
      1904995..1905195 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_389653.2 spore coat protein (outer) [Bacillus subtilis subsp. subtilis str. 168]

      See identical proteins and their annotated locations for NP_389653.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P07790
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P07790.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases