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    pyrR transcriptional attenuator and uracil phosphoribosyltransferase activity [ Bacillus subtilis subsp. subtilis str. 168 ]

    Gene ID: 938030, updated on 12-Feb-2021

    Summary

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    Gene symbol
    pyrR
    Gene description
    transcriptional attenuator and uracil phosphoribosyltransferase activity
    Locus tag
    BSU_15470
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
    Lineage
    Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
    Old locus tag
    BSU15470
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    Genomic context

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    Sequence:
    NC_000964.3 (1618304..1618849)

    NC_000964.3Genomic Context describing neighboring genes Neighboring gene pseudouridylate synthase Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene uracil permease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000964.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The regulator protein PyrR of Bacillus subtilis specifically interacts in vivo with three untranslated regions within pyr mRNA of pyrimidine biosynthesis. Hobl B, et al. Microbiology (Reading), 2007 Mar. PMID 17322189
    2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
    3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
    4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
    5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. results indicate that PyrR specifically binds to the binding loops BL1, BL2 and BL3 which are within three untranslated leader sequences at the beginning of pyr mRNA
      Title: The regulator protein PyrR of Bacillus subtilis specifically interacts in vivo with three untranslated regions within pyr mRNA of pyrimidine biosynthesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    transcriptional attenuator and uracil phosphoribosyltransferase activity
    NP_389430.1
    • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 7798145, 9932459, 12482852, 15716449, 17322189, 18678934; Product type r : regulator

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000964.3 Reference assembly

      Range
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_389430.1 transcriptional attenuator and uracil phosphoribosyltransferase activity [Bacillus subtilis subsp. subtilis str. 168]

      See identical proteins and their annotated locations for NP_389430.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P39765
      Conserved Domains (1) summary
      PRK05205
      Location:2 → 179
      PRK05205; bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39765.2

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases
    Research Materials