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    der GTPase essential for ribosome 50S subunit assembly (maturation of the 50S subunit central protoberance) [ Bacillus subtilis subsp. subtilis str. 168 ]

    Gene ID: 938988, updated on 12-Feb-2021

    Summary

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    Gene symbol
    der
    Gene description
    GTPase essential for ribosome 50S subunit assembly (maturation of the 50S subunit central protoberance)
    Locus tag
    BSU_22840
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
    Lineage
    Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
    Old locus tag
    BSU22840
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    Genomic context

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    Sequence:
    NC_000964.3 (2390206..2391516, complement)

    NC_000964.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene NADPH-dependent glycerol-3-phosphate dehydrogenase Neighboring gene hypothetical protein Neighboring gene conserved membrane protein of unknown function Neighboring gene conserved membrane protein of unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000964.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning, purification and preliminary crystallographic analysis of the Bacillus subtilis GTPase YphC-GDP complex. Xu L, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2006 May 1. PMID 16682769, Free PMC Article
    2. Multiple GTPases participate in the assembly of the large ribosomal subunit in Bacillus subtilis. Schaefer L, et al. J Bacteriol, 2006 Dec. PMID 16997968, Free PMC Article
    3. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
    4. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
    5. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. are required for large ribosomal subunit biogenesis in B.subtilis
      Title: Multiple GTPases participate in the assembly of the large ribosomal subunit in Bacillus subtilis.
    2. cloned, overexpressed, purified, crystallized and collected a multiple-wavelength anomalous diffraction (MAD) data set to 2.5 A resolution of YphC in complex with GDP
      Title: Cloning, purification and preliminary crystallographic analysis of the Bacillus subtilis GTPase YphC-GDP complex.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    GTPase essential for ribosome 50S subunit assembly (maturation of the 50S subunit central protoberance)
    NP_390165.1
    • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 16682769, 16894162, 16997968, 19246542, 23056455, 24822275, 27484475; Product type e: enzyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000964.3 Reference assembly

      Range
      2390206..2391516 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_390165.1 GTPase essential for ribosome 50S subunit assembly (maturation of the 50S subunit central protoberance) [Bacillus subtilis subsp. subtilis str. 168]

      See identical proteins and their annotated locations for NP_390165.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P50743
      Conserved Domains (1) summary
      PRK00093
      Location:3 → 436
      PRK00093; GTP-binding protein Der; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    5M7H_A.1
    P50743.1

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    Other Literature Sources
    Molecular Biology Databases