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    mid2 septin ring organizing protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542683, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mid2
    Official Full Name
    septin ring organizing protein
    Primary source
    PomBase:SPAPYUG7.03c
    Locus tag
    SPOM_SPAPYUG7.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mid2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4748861..4751453, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MAP kinase-interacting protein Sin1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-directed RNA polymerase II complex TFIIS subunit Rpb9 Neighboring gene ncRNA Neighboring gene delta-1-pyrroline-5-carboxylate reductase Neighboring gene PPPDE peptidase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation. Tasto JJ, et al. J Cell Biol, 2003 Mar 31. PMID 12668659, Free PMC Article
    2. Mid2p stabilizes septin rings during cytokinesis in fission yeast. Berlin A, et al. J Cell Biol, 2003 Mar 31. PMID 12654901, Free PMC Article
    3. Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis. Hachet O, et al. Genes Dev, 2008 Nov 15. PMID 19056897, Free PMC Article
    4. Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression. Petit CS, et al. J Cell Sci, 2005 Dec 15. PMID 16317047
    5. Role of septins and the exocyst complex in the function of hydrolytic enzymes responsible for fission yeast cell separation. Martín-Cuadrado AB, et al. Mol Biol Cell, 2005 Oct. PMID 16079182, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis.
      Title: Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis.
    2. Mid2p production is controlled by Ace2p functioning downstream of Sep1p.
      Title: Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatidylinositol-4,5-bisphosphate binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in septin ring organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in septin ring organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in medial cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in medial cortex septin ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in split septin rings IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    septin ring organizing protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4748861..4751453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020131.3 → NP_594704.2  septin ring organizing protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594704.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q8X1T2, Q9P7Y8
      Conserved Domains (2) summary
      cd13278
      Location:567 → 699
      PH_Bud4; Bud4 Pleckstrin homology (PH) domain
      pfam00169
      Location:584 → 687
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version

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