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    edc1 protein Edc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542536, updated on 18-Sep-2024

    Summary

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    Official Symbol
    edc1
    Official Full Name
    protein Edc1
    Primary source
    PomBase:SPAC18G6.09c
    Locus tag
    SPOM_SPAC18G6.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    dbs1
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    Genomic context

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    See edc1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2231661..2234160, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene rRNA (pseudouridine) methyltransferase Mra1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene LEM domain nuclear inner membrane protein Heh1/Lem2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme. Wurm JP, et al. Proc Natl Acad Sci U S A, 2017 Jun 6. PMID 28533364, Free PMC Article
    2. Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Valkov E, et al. Nat Struct Mol Biol, 2016 Jun. PMID 27183195
    3. The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface. Wurm JP, et al. RNA, 2016 Sep. PMID 27354705, Free PMC Article
    4. The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex. Fromm SA, et al. EMBO J, 2012 Jan 18. PMID 22085934, Free PMC Article
    5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables mRNA phosphatase activator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables mRNA phosphatase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA methylguanosine-cap decapping IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA decapping complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    protein Edc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2231661..2234160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019104.3 → NP_593672.1  protein Edc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593672.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10108
      Conserved Domains (1) summary
      pfam15365
      Location:157 → 212
      PNRC; Proline-rich nuclear receptor coactivator
    Nucleotide Protein
    Heading Accession and Version

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