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    lys7 alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542118, updated on 18-Sep-2024

    Summary

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    Official Symbol
    lys7
    Official Full Name
    alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7
    Primary source
    PomBase:SPAC17C9.02c
    Locus tag
    SPOM_SPAC17C9.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See lys7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4496725..4498140)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit Med27 Neighboring gene translation initiation factor eIF4G Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anaphase-promoting complex TPR lobe subcomplex subunit Apc3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Posttranslational activation, site-directed mutation and phylogenetic analyses of the lysine biosynthesis enzymes alpha-aminoadipate reductase Lys1p (AAR) and the phosphopantetheinyl transferase Lys7p (PPTase) from Schizosaccharomyces pombe. Guo S, et al. Yeast, 2004 Nov. PMID 15546125
    2. Functional characterization of 4'-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5. Mootz HD, et al. FEMS Microbiol Lett, 2002 Jul 16. PMID 12127488
    3. Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe. Ye ZH, et al. J Bacteriol, 1988 Dec. PMID 3142867, Free PMC Article
    4. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables holo-[acyl-carrier-protein] synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables holo-[acyl-carrier-protein] synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in lysine biosynthetic process via aminoadipic acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lysine biosynthetic process via aminoadipic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4496725..4498140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020031.3 → NP_594603.1  alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594603.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10474
      Conserved Domains (2) summary
      COG2091
      Location:3 → 243
      Sfp; Phosphopantetheinyl transferase [Coenzyme transport and metabolism]
      cl00500
      Location:122 → 214
      ACPS; 4'-phosphopantetheinyl transferase superfamily
    Nucleotide Protein
    Heading Accession and Version

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