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    TTC24 tetratricopeptide repeat domain 24 [ Homo sapiens (human) ]

    Gene ID: 164118, updated on 17-Sep-2024

    Summary

    Official Symbol
    TTC24provided by HGNC
    Official Full Name
    tetratricopeptide repeat domain 24provided by HGNC
    Primary source
    HGNC:HGNC:32348
    See related
    Ensembl:ENSG00000187862 AllianceGenome:HGNC:32348
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in lymph node (RPKM 3.0), spleen (RPKM 1.9) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See TTC24 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (156579723..156587719)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (155716091..155724195)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (156549515..156557511)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156432711-156433660 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156445026-156445638 Neighboring gene myocyte enhancer factor 2D Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1863 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1864 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1865 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1866 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1867 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156466171-156466671 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1428 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156471045-156471824 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1429 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1868 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:156474933-156475335 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1870 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1869 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:156483472-156483678 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1430 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:156495835-156496406 Neighboring gene small nucleolar RNA U13 Neighboring gene IQ motif containing GTPase activating protein 3 Neighboring gene NANOG hESC enhancer GRCh37_chr1:156508711-156509291 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1871 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1872 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1873 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156554411-156554912 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156554913-156555412 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156561722-156562568 Neighboring gene G-patch domain containing 4 (gene/pseudogene) Neighboring gene NAD(P)HX epimerase

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    tetratricopeptide repeat protein 24
    Names
    TPR repeat protein 24

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105669.4NP_001099139.2  tetratricopeptide repeat protein 24

      See identical proteins and their annotated locations for NP_001099139.2

      Status: VALIDATED

      Source sequence(s)
      AL365181
      Consensus CDS
      CCDS53379.1
      UniProtKB/Swiss-Prot
      A2A3L6, Q5T3H7
      Related
      ENSP00000357219.3, ENST00000368236.8
      Conserved Domains (5) summary
      smart00028
      Location:273302
      TPR; Tetratricopeptide repeats
      sd00006
      Location:273301
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:353380
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:121180
      TPR_11; TPR repeat
      pfam13424
      Location:271345
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      156579723..156587719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047447969.1XP_047303925.1  tetratricopeptide repeat protein 24 isoform X3

    2. XM_011509253.3XP_011507555.2  tetratricopeptide repeat protein 24 isoform X1

    3. XM_011509255.3XP_011507557.2  tetratricopeptide repeat protein 24 isoform X4

    4. XM_047447973.1XP_047303929.1  tetratricopeptide repeat protein 24 isoform X6

    5. XM_011509254.3XP_011507556.2  tetratricopeptide repeat protein 24 isoform X2

    6. XM_047447971.1XP_047303927.1  tetratricopeptide repeat protein 24 isoform X5

    7. XM_047447977.1XP_047303933.1  tetratricopeptide repeat protein 24 isoform X8

    8. XM_047447975.1XP_047303931.1  tetratricopeptide repeat protein 24 isoform X7

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791758.1 Reference GRCh38.p14 PATCHES

      Range
      138280..146384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054332835.1XP_054188810.1  tetratricopeptide repeat protein 24 isoform X3

    2. XM_054332840.1XP_054188815.1  tetratricopeptide repeat protein 24 isoform X8

    3. XM_054332833.1XP_054188808.1  tetratricopeptide repeat protein 24 isoform X1

    4. XM_054332836.1XP_054188811.1  tetratricopeptide repeat protein 24 isoform X4

    5. XM_054332838.1XP_054188813.1  tetratricopeptide repeat protein 24 isoform X6

    6. XM_054332834.1XP_054188809.1  tetratricopeptide repeat protein 24 isoform X2

    7. XM_054332837.1XP_054188812.1  tetratricopeptide repeat protein 24 isoform X5

    8. XM_054332839.1XP_054188814.1  tetratricopeptide repeat protein 24 isoform X7

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      155716091..155724195
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054334786.1XP_054190761.1  tetratricopeptide repeat protein 24 isoform X3

    2. XM_054334791.1XP_054190766.1  tetratricopeptide repeat protein 24 isoform X8

    3. XM_054334784.1XP_054190759.1  tetratricopeptide repeat protein 24 isoform X1

    4. XM_054334787.1XP_054190762.1  tetratricopeptide repeat protein 24 isoform X4

    5. XM_054334789.1XP_054190764.1  tetratricopeptide repeat protein 24 isoform X6

    6. XM_054334785.1XP_054190760.1  tetratricopeptide repeat protein 24 isoform X2

    7. XM_054334788.1XP_054190763.1  tetratricopeptide repeat protein 24 isoform X5

    8. XM_054334790.1XP_054190765.1  tetratricopeptide repeat protein 24 isoform X7

    RNA

    1. XR_008485940.1 RNA Sequence