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    RMP1 Rmp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850837, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RMP1
    Official Full Name
    Rmp1p
    Primary source
    SGD:S000004135
    Locus tag
    YLR145W
    See related
    AllianceGenome:SGD:S000004135; FungiDB:YLR145W; VEuPathDB:YLR145W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables rRNA primary transcript binding activity. Involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay. Located in cytoplasm and nucleolus. Part of ribonuclease MRP complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RMP1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (432168..432773)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene diphthine--ammonia ligase Neighboring gene endo-1,3(4)-beta-glucanase Neighboring gene spermine synthase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A specialized processing body that is temporally and asymmetrically regulated during the cell cycle in Saccharomyces cerevisiae. Gill T, et al. J Cell Biol, 2006 Apr 10. PMID 16585272, Free PMC Article
    2. Disruption of six Saccharomyces cerevisiae ORFs on chromosome XII results in three lethal disruptants. Alloush HM, et al. Yeast, 2002 Jan 15. PMID 11754485
    3. Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP. Perederina A, et al. Nat Commun, 2020 Jul 10. PMID 32651392, Free PMC Article
    4. Interactions between subunits of Saccharomyces cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP architecture. Aspinall TV, et al. Nucleic Acids Res, 2007. PMID 17881380, Free PMC Article
    5. Characterization and purification of Saccharomyces cerevisiae RNase MRP reveals a new unique protein component. Salinas K, et al. J Biol Chem, 2005 Mar 25. PMID 15637077

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rRNA primary transcript binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA primary transcript binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA primary transcript binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA catabolic process, RNase MRP-dependent IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear-transcribed mRNA catabolic process, RNase MRP-dependent IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease MRP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonuclease MRP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonuclease MRP complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Rmp1p
    NP_013246.1
    • Subunit of RNase MRP; RNase MRP processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; unlike most subunits, not shared between RNase MRP and nuclear RNase P

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      432168..432773
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182032.1 → NP_013246.1  TPA: Rmp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013246.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYD9, Q12530
      UniProtKB/TrEMBL
      B3LTA5, C8ZDB4, G2WIY3, N1P6N8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12530.1

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