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    OAF out at first homolog [ Homo sapiens (human) ]

    Gene ID: 220323, updated on 17-Sep-2024

    Summary

    Official Symbol
    OAFprovided by HGNC
    Official Full Name
    out at first homologprovided by HGNC
    Primary source
    HGNC:HGNC:28752
    See related
    Ensembl:ENSG00000184232 AllianceGenome:HGNC:28752
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NS5ATP13TP2
    Expression
    Ubiquitous expression in liver (RPKM 56.8), colon (RPKM 31.5) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See OAF in Genome Data Viewer
    Location:
    11q23.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (120211032..120230334)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (120233870..120253135)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (120081740..120101043)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902773 Neighboring gene uncharacterized LOC105369530 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:120067578-120068078 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:120068079-120068579 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:120080493-120081034 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3986 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3987 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3988 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:120088347-120088930 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:120091419-120091918 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:120105831-120106053 Neighboring gene POU class 2 homeobox 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:120119877-120120516 Neighboring gene Sharpr-MPRA regulatory region 564 Neighboring gene uncharacterized LOC649133 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:120135803-120135974 Neighboring gene uncharacterized LOC105369531 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:120146894-120147083

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC52117

    General protein information

    Preferred Names
    out at first protein homolog
    Names
    HCV NS5A-transactivated protein 13 target protein 2
    OAF homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178507.4NP_848602.1  out at first protein homolog precursor

      See identical proteins and their annotated locations for NP_848602.1

      Status: VALIDATED

      Source sequence(s)
      AA902624, AI733095, AP000679, BC047726, DB480792
      Consensus CDS
      CCDS8430.1
      UniProtKB/Swiss-Prot
      Q86UD1
      Related
      ENSP00000332613.3, ENST00000328965.9
      Conserved Domains (1) summary
      pfam14941
      Location:31268
      OAF; Transcriptional regulator, Out at first

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      120211032..120230334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      120233870..120253135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)