CNOT3 CCR4-NOT transcription complex subunit 3 [Homo sapiens (human)] - Gene

Summary

Official Symbol: CNOT3provided by HGNC
Official Full Name: CCR4-NOT transcription complex subunit 3provided by HGNC
Primary source: HGNC:HGNC:7879
See related: Ensembl:ENSG00000088038 MIM:604910; AllianceGenome:HGNC:7879
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: NOT3; LENG2; NOT3H; IDDSADF
Summary: Involved in regulation of stem cell population maintenance. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in testis (RPKM 13.9), spleen (RPKM 9.7) and 25 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 19q13.42

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	19	NC_000019.10 (54137762..54155681)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	19	NC_060943.1 (57217961..57235947)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	19	NC_000019.9 (54641478..54659419)

Chromosome 19 - NC_000019.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis.
Title: Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis.
CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
Title: CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients.
Title: Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients.
CNOT3 interacts with the Aurora B and MAPK/ERK kinases to promote survival of differentiating mesendodermal progenitor cells.
Title: CNOT3 interacts with the Aurora B and MAPK/ERK kinases to promote survival of differentiating mesendodermal progenitor cells.
Determinants of Disease Penetrance in PRPF31-Associated Retinopathy.
Title: Determinants of Disease Penetrance in PRPF31-Associated Retinopathy.
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
Title: A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
Inherited cases of CNOT3-associated intellectual developmental disorder with speech delay, autism, and dysmorphic facies.
Title: Inherited cases of CNOT3-associated intellectual developmental disorder with speech delay, autism, and dysmorphic facies.
The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy.
Title: The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy.
De novo variants in CNOT3 cause a variable neurodevelopmental disorder.
Title: De novo variants in CNOT3 cause a variable neurodevelopmental disorder.
CCR4-NOT transcription complex subunit 3 (CNOT3) is up-regulated in lung cancer tissues and is associated with poor prognosis of the patients. Knocking down CNOT3 expression sensitizes cisplatin-resistant A549 (A549/DDP) cells to cisplatin-induced apoptosis. CNOT3 depletion up-regulates the expression level of RIPK3 and the enhanced apoptosis is mediated by the elevated RIPK3 to further trigger Caspase 8 activation.
Title: CNOT3 contributes to cisplatin resistance in lung cancer through inhibiting RIPK3 expression.

Submit: New GeneRIF Correction See all GeneRIFs (23)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Intellectual developmental disorder with speech delay, autism, and dysmorphic facies MedGen: C5231456 OMIM: 618672 GeneReviews: Not available	not available

Copy number response

Description
Copy number response Haploinsufficency No evidence available (Last evaluated 2018-06-27) ClinGen Genome Curation Page Triplosensitivity No evidence available (Last evaluated 2018-06-27) ClinGen Genome Curation Page

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

REN91714 (e-PCR)
- UniSTS:416512

REN91715 (e-PCR)
- UniSTS:416513

REN91716 (e-PCR)
- UniSTS:416514

REN91717 (e-PCR)
- UniSTS:416515

REN91718 (e-PCR)
- UniSTS:416516

REN91719 (e-PCR)
- UniSTS:416517

REN91720 (e-PCR)
- UniSTS:416518

REN91721 (e-PCR)
- UniSTS:416519

REN91722 (e-PCR)
- UniSTS:416520

REN91723 (e-PCR)
- UniSTS:416521

REN91724 (e-PCR)
- UniSTS:416522

REN91725 (e-PCR)
- UniSTS:416523

REN91726 (e-PCR)
- UniSTS:416524

REN91727 (e-PCR)
- UniSTS:416525

REN91728 (e-PCR)
- UniSTS:416526

REN91729 (e-PCR)
- UniSTS:416527

REN91730 (e-PCR)
- UniSTS:416528

REN91731 (e-PCR)
- UniSTS:416529

ECD04123 (e-PCR)
- UniSTS:285202

REN91732 (e-PCR)
- UniSTS:416530

REN91733 (e-PCR)
- UniSTS:416531

REN91734 (e-PCR)
- UniSTS:416532

REN91735 (e-PCR)
- UniSTS:416533

REN91736 (e-PCR)
- UniSTS:416534

REN91737 (e-PCR)
- UniSTS:416535

REN91738 (e-PCR)
- UniSTS:416536

REN91739 (e-PCR)
- UniSTS:416537

ECD20077 (e-PCR)
- UniSTS:301081

REN91740 (e-PCR)
- UniSTS:416538

REN91741 (e-PCR)
- UniSTS:416539

REN91742 (e-PCR)
- UniSTS:416540

REN91743 (e-PCR)
- UniSTS:416541

REN91744 (e-PCR)
- UniSTS:416542

ECD06200 (e-PCR)
- UniSTS:287262

REN91745 (e-PCR)
- UniSTS:416543

REN91746 (e-PCR)
- UniSTS:416544

REN91747 (e-PCR)
- UniSTS:416545

REN91748 (e-PCR)
- UniSTS:416546

REN91749 (e-PCR)
- UniSTS:416547

REN91750 (e-PCR)
- UniSTS:416548

REN91751 (e-PCR)
- UniSTS:416549

REN91752 (e-PCR)
- UniSTS:416550

REN91753 (e-PCR)
- UniSTS:416551

G67807 (e-PCR)
- UniSTS:225582

ECD13418 (e-PCR)
- UniSTS:294448

ECD20107 (e-PCR)
- UniSTS:301111

ECD00295 (e-PCR)
- UniSTS:281408

ECD06234 (e-PCR)
- UniSTS:287296

ECD06494 (e-PCR)
- UniSTS:287554

ECD04958 (e-PCR)
- UniSTS:286026

ECD22462 (e-PCR)
- UniSTS:303448

ECD19132 (e-PCR)
- UniSTS:300139

ECD03956 (e-PCR)
- UniSTS:285036

ECD13498 (e-PCR)
- UniSTS:294527

ECD00878 (e-PCR)
- UniSTS:281987

ECD06050 (e-PCR)
- UniSTS:287112

ECD05030 (e-PCR)
- UniSTS:286096

ECD05806 (e-PCR)
- UniSTS:286868

ECD14557 (e-PCR)
- UniSTS:295577

ECD05310 (e-PCR)
- UniSTS:286376

ECD10727 (e-PCR)
- UniSTS:291766

ECD01208 (e-PCR)
- UniSTS:282315

REN91664 (e-PCR)
- UniSTS:416462

REN91665 (e-PCR)
- UniSTS:416463

REN91666 (e-PCR)
- UniSTS:416464

REN91667 (e-PCR)
- UniSTS:416465

REN91668 (e-PCR)
- UniSTS:416466

REN91669 (e-PCR)
- UniSTS:416467

REN91670 (e-PCR)
- UniSTS:416468

REN91671 (e-PCR)
- UniSTS:416469

REN91672 (e-PCR)
- UniSTS:416470

REN91673 (e-PCR)
- UniSTS:416471

REN91674 (e-PCR)
- UniSTS:416472

REN91675 (e-PCR)
- UniSTS:416473

ECD05103 (e-PCR)
- UniSTS:286169

REN91676 (e-PCR)
- UniSTS:416474

REN91677 (e-PCR)
- UniSTS:416475

REN91678 (e-PCR)
- UniSTS:416476

stSG605831 (e-PCR)
- UniSTS:447964

REN91679 (e-PCR)
- UniSTS:416477

REN91680 (e-PCR)
- UniSTS:416478

REN91681 (e-PCR)
- UniSTS:416479

REN91682 (e-PCR)
- UniSTS:416480

REN91683 (e-PCR)
- UniSTS:416481

REN91684 (e-PCR)
- UniSTS:416482

REN91685 (e-PCR)
- UniSTS:416483

REN91686 (e-PCR)
- UniSTS:416484

REN91687 (e-PCR)
- UniSTS:416485

REN91688 (e-PCR)
- UniSTS:416486

REN91689 (e-PCR)
- UniSTS:416487

REN91690 (e-PCR)
- UniSTS:416488

REN91691 (e-PCR)
- UniSTS:416489

REN91692 (e-PCR)
- UniSTS:416490

REN91693 (e-PCR)
- UniSTS:416491

REN91694 (e-PCR)
- UniSTS:416492

REN91695 (e-PCR)
- UniSTS:416493

REN91696 (e-PCR)
- UniSTS:416494

REN91697 (e-PCR)
- UniSTS:416495

REN91698 (e-PCR)
- UniSTS:416496

REN91699 (e-PCR)
- UniSTS:416497

REN91700 (e-PCR)
- UniSTS:416498

REN91701 (e-PCR)
- UniSTS:416499

REN91702 (e-PCR)
- UniSTS:416500

REN91703 (e-PCR)
- UniSTS:416501

ECD05646 (e-PCR)
- UniSTS:286709

REN91704 (e-PCR)
- UniSTS:416502

REN91705 (e-PCR)
- UniSTS:416503

REN91706 (e-PCR)
- UniSTS:416504

REN91707 (e-PCR)
- UniSTS:416505

REN91708 (e-PCR)
- UniSTS:416506

REN91709 (e-PCR)
- UniSTS:416507

REN91710 (e-PCR)
- UniSTS:416508

REN91711 (e-PCR)
- UniSTS:416509

ECD01259 (e-PCR)
- UniSTS:282366

REN91712 (e-PCR)
- UniSTS:416510

REN91713 (e-PCR)
- UniSTS:416511

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in nuclear-transcribed mRNA poly(A) tail shortening	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear-transcribed mRNA poly(A) tail shortening	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of cold-induced thermogenesis	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of stem cell population maintenance	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of stem cell population maintenance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of translation	IEA Inferred from Electronic Annotation more info
involved_in regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info
involved_in trophectodermal cell differentiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CCR4-NOT complex	IDA Inferred from Direct Assay more info	PubMed
part_of CCR4-NOT complex	NAS Non-traceable Author Statement more info	PubMed
part_of CCR4-NOT core complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in P-body	IBA Inferred from Biological aspect of Ancestor more info
located_in P-body	ISS Inferred from Sequence or Structural Similarity more info
located_in cytosol	TAS Traceable Author Statement more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CCR4-NOT transcription complex subunit 3

Names: CCR4-associated factor 3; NOT3 (negative regulator of transcription 3, yeast) homolog; leukocyte receptor cluster member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_014516.4 → NP_055331.1 CCR4-NOT transcription complex subunit 3

See identical proteins and their annotated locations for NP_055331.1

Status: VALIDATED

Source sequence(s)

AC245052

Consensus CDS

CCDS12880.1

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

UniProtKB/TrEMBL

B7Z6J7

Related

ENSP00000221232.5, ENST00000221232.11

Conserved Domains (2) summary

COG5665
Location:12 → 751

COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]

pfam04065
Location:3 → 229

Not3; Not1 N-terminal domain, CCR4-Not complex component

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000019.10 Reference GRCh38.p14 Primary Assembly

Range

54137762..54155681

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047438877.1 → XP_047294833.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_047438878.1 → XP_047294834.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_047438866.1 → XP_047294822.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_047438874.1 → XP_047294830.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_047438879.1 → XP_047294835.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_005278280.3 → XP_005278337.1 CCR4-NOT transcription complex subunit 3 isoform X1

See identical proteins and their annotated locations for XP_005278337.1

UniProtKB/TrEMBL

B7Z6J7

Conserved Domains (2) summary

COG5665
Location:12 → 769

COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]

pfam04065
Location:3 → 230

Not3; Not1 N-terminal domain, CCR4-Not complex component
XM_047438872.1 → XP_047294828.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_047438867.1 → XP_047294823.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_047438875.1 → XP_047294831.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Related

ENSP00000351159.4, ENST00000358389.7
XM_005278279.3 → XP_005278336.1 CCR4-NOT transcription complex subunit 3 isoform X1

See identical proteins and their annotated locations for XP_005278336.1

UniProtKB/TrEMBL

B7Z6J7

Conserved Domains (2) summary

COG5665
Location:12 → 769

COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]

pfam04065
Location:3 → 230

Not3; Not1 N-terminal domain, CCR4-Not complex component
XM_005278282.4 → XP_005278339.1 CCR4-NOT transcription complex subunit 3 isoform X5

See identical proteins and their annotated locations for XP_005278339.1

UniProtKB/TrEMBL

B7Z6J7

Conserved Domains (2) summary

COG5665
Location:12 → 752

COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]

pfam04065
Location:3 → 230

Not3; Not1 N-terminal domain, CCR4-Not complex component
XM_005278281.3 → XP_005278338.1 CCR4-NOT transcription complex subunit 3 isoform X2

See identical proteins and their annotated locations for XP_005278338.1

UniProtKB/TrEMBL

B7Z6J7

Conserved Domains (2) summary

COG5665
Location:12 → 768

COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]

pfam04065
Location:3 → 229

Not3; Not1 N-terminal domain, CCR4-Not complex component
XM_047438869.1 → XP_047294825.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_047438871.1 → XP_047294827.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_047438880.1 → XP_047294836.1 CCR4-NOT transcription complex subunit 3 isoform X8

Related

ENSP00000496602.1, ENST00000617930.2
XM_047438870.1 → XP_047294826.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_011526993.4 → XP_011525295.1 CCR4-NOT transcription complex subunit 3 isoform X7

See identical proteins and their annotated locations for XP_011525295.1

UniProtKB/TrEMBL

B7Z6J7

Conserved Domains (2) summary

pfam04065
Location:3 → 230

Not3; Not1 N-terminal domain, CCR4-Not complex component

cl02384
Location:625 → 678

NOT2_3_5; NOT2 / NOT3 / NOT5 family
XM_047438868.1 → XP_047294824.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_047438873.1 → XP_047294829.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_047438876.1 → XP_047294832.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

NW_003571054.1 Reference GRCh38.p14 ALT_REF_LOCI_1

Range

112518..130531

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054329698.1 → XP_054185673.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054329685.1 → XP_054185660.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054329694.1 → XP_054185669.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054329687.1 → XP_054185662.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054329695.1 → XP_054185670.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054329684.1 → XP_054185659.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054329693.1 → XP_054185668.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054329686.1 → XP_054185661.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054329690.1 → XP_054185665.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054329692.1 → XP_054185667.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054329689.1 → XP_054185664.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054329691.1 → XP_054185666.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054329699.1 → XP_054185674.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054329697.1 → XP_054185672.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054329688.1 → XP_054185663.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054329696.1 → XP_054185671.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

NW_003571055.2 Reference GRCh38.p14 ALT_REF_LOCI_2

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330191.1 → XP_054186166.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330195.1 → XP_054186170.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330181.1 → XP_054186156.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330180.1 → XP_054186155.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330189.1 → XP_054186164.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330183.1 → XP_054186158.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330192.1 → XP_054186167.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330179.1 → XP_054186154.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330188.1 → XP_054186163.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330182.1 → XP_054186157.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330198.1 → XP_054186173.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330187.1 → XP_054186162.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054330185.1 → XP_054186160.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054330197.1 → XP_054186172.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330186.1 → XP_054186161.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054330196.1 → XP_054186171.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054330184.1 → XP_054186159.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330190.1 → XP_054186165.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330193.1 → XP_054186168.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330194.1 → XP_054186169.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

NW_003571056.2 Reference GRCh38.p14 ALT_REF_LOCI_3

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330492.1 → XP_054186467.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330478.1 → XP_054186453.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330477.1 → XP_054186452.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330487.1 → XP_054186462.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330480.1 → XP_054186455.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330490.1 → XP_054186465.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330476.1 → XP_054186451.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330486.1 → XP_054186461.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330479.1 → XP_054186454.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330496.1 → XP_054186471.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330485.1 → XP_054186460.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054330483.1 → XP_054186458.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054330495.1 → XP_054186470.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330484.1 → XP_054186459.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054330494.1 → XP_054186469.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054330481.1 → XP_054186456.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330488.1 → XP_054186463.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330491.1 → XP_054186466.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330482.1 → XP_054186457.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330489.1 → XP_054186464.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330493.1 → XP_054186468.1 CCR4-NOT transcription complex subunit 3 isoform X9

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

NW_003571057.2 Reference GRCh38.p14 ALT_REF_LOCI_4

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330739.1 → XP_054186714.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330743.1 → XP_054186718.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330729.1 → XP_054186704.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330737.1 → XP_054186712.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330731.1 → XP_054186706.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330740.1 → XP_054186715.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330728.1 → XP_054186703.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330736.1 → XP_054186711.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330730.1 → XP_054186705.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330745.1 → XP_054186720.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330734.1 → XP_054186709.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054330735.1 → XP_054186710.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054330744.1 → XP_054186719.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054330732.1 → XP_054186707.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330738.1 → XP_054186713.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330742.1 → XP_054186717.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330733.1 → XP_054186708.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330741.1 → XP_054186716.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

NW_003571058.2 Reference GRCh38.p14 ALT_REF_LOCI_5

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330969.1 → XP_054186944.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330971.1 → XP_054186946.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330960.1 → XP_054186935.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330967.1 → XP_054186942.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330962.1 → XP_054186937.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330970.1 → XP_054186945.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330959.1 → XP_054186934.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054330966.1 → XP_054186941.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330961.1 → XP_054186936.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330976.1 → XP_054186951.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330964.1 → XP_054186939.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054330975.1 → XP_054186950.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054330965.1 → XP_054186940.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054330974.1 → XP_054186949.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054330968.1 → XP_054186943.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054330973.1 → XP_054186948.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054330963.1 → XP_054186938.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054330972.1 → XP_054186947.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

NW_003571059.2 Reference GRCh38.p14 ALT_REF_LOCI_6

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054331252.1 → XP_054187227.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331254.1 → XP_054187229.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054331242.1 → XP_054187217.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054331241.1 → XP_054187216.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054331251.1 → XP_054187226.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331244.1 → XP_054187219.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054331253.1 → XP_054187228.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054331240.1 → XP_054187215.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054331250.1 → XP_054187225.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331243.1 → XP_054187218.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054331259.1 → XP_054187234.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054331249.1 → XP_054187224.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054331247.1 → XP_054187222.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054331258.1 → XP_054187233.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054331248.1 → XP_054187223.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054331257.1 → XP_054187232.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054331245.1 → XP_054187220.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054331255.1 → XP_054187230.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054331246.1 → XP_054187221.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054331256.1 → XP_054187231.1 CCR4-NOT transcription complex subunit 3 isoform X10

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

NW_003571060.1 Reference GRCh38.p14 ALT_REF_LOCI_7

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054331525.1 → XP_054187500.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331528.1 → XP_054187503.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054331517.1 → XP_054187492.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054331516.1 → XP_054187491.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054331523.1 → XP_054187498.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331519.1 → XP_054187494.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054331526.1 → XP_054187501.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054331515.1 → XP_054187490.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054331522.1 → XP_054187497.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331518.1 → XP_054187493.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054331520.1 → XP_054187495.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054331521.1 → XP_054187496.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054331529.1 → XP_054187504.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054331524.1 → XP_054187499.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054331527.1 → XP_054187502.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_8

Genomic

NW_003571061.2 Reference GRCh38.p14 ALT_REF_LOCI_8

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054333570.1 → XP_054189545.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054333556.1 → XP_054189531.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054333565.1 → XP_054189540.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333558.1 → XP_054189533.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333568.1 → XP_054189543.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054333555.1 → XP_054189530.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054333564.1 → XP_054189539.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333557.1 → XP_054189532.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333563.1 → XP_054189538.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054333561.1 → XP_054189536.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054333573.1 → XP_054189548.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054333562.1 → XP_054189537.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054333572.1 → XP_054189547.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054333559.1 → XP_054189534.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333566.1 → XP_054189541.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333571.1 → XP_054189546.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054333560.1 → XP_054189535.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333567.1 → XP_054189542.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333569.1 → XP_054189544.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Reference GRCh38.p14 ALT_REF_LOCI_9

Genomic

NT_187693.1 Reference GRCh38.p14 ALT_REF_LOCI_9

Range

112518..130532

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054333668.1 → XP_054189643.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333671.1 → XP_054189646.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054333658.1 → XP_054189633.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054333656.1 → XP_054189631.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054333666.1 → XP_054189641.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333660.1 → XP_054189635.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333669.1 → XP_054189644.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054333657.1 → XP_054189632.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054333665.1 → XP_054189640.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333659.1 → XP_054189634.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333675.1 → XP_054189650.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054333664.1 → XP_054189639.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054333662.1 → XP_054189637.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054333674.1 → XP_054189649.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054333663.1 → XP_054189638.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054333673.1 → XP_054189648.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054333661.1 → XP_054189636.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054333667.1 → XP_054189642.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054333672.1 → XP_054189647.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054333670.1 → XP_054189645.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76

Alternate T2T-CHM13v2.0

Genomic

NC_060943.1 Alternate T2T-CHM13v2.0

Range

57217961..57235947

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054321095.1 → XP_054177070.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054321098.1 → XP_054177073.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054321099.1 → XP_054177074.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054321082.1 → XP_054177057.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054321094.1 → XP_054177069.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054321100.1 → XP_054177075.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054321081.1 → XP_054177056.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054321092.1 → XP_054177067.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054321084.1 → XP_054177059.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054321096.1 → XP_054177071.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054321080.1 → XP_054177055.1 CCR4-NOT transcription complex subunit 3 isoform X1
XM_054321091.1 → XP_054177066.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054321083.1 → XP_054177058.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054321088.1 → XP_054177063.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054321103.1 → XP_054177078.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054321090.1 → XP_054177065.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054321087.1 → XP_054177062.1 CCR4-NOT transcription complex subunit 3 isoform X3
XM_054321102.1 → XP_054177077.1 CCR4-NOT transcription complex subunit 3 isoform X8
XM_054321089.1 → XP_054177064.1 CCR4-NOT transcription complex subunit 3 isoform X4
XM_054321101.1 → XP_054177076.1 CCR4-NOT transcription complex subunit 3 isoform X7
XM_054321085.1 → XP_054177060.1 CCR4-NOT transcription complex subunit 3 isoform X2
XM_054321093.1 → XP_054177068.1 CCR4-NOT transcription complex subunit 3 isoform X5
XM_054321097.1 → XP_054177072.1 CCR4-NOT transcription complex subunit 3 isoform X6

UniProtKB/Swiss-Prot

O75175, Q9NZN7, Q9UF76
XM_054321086.1 → XP_054177061.1 CCR4-NOT transcription complex subunit 3 isoform X2