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    DPY19L2P1 DPY19L2 pseudogene 1 [ Homo sapiens (human) ]

    Gene ID: 554236, updated on 28-Oct-2024

    Summary

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    Official Symbol
    DPY19L2P1provided by HGNC
    Official Full Name
    DPY19L2 pseudogene 1provided by HGNC
    Primary source
    HGNC:HGNC:22305
    See related
    Ensembl:ENSG00000291133 AllianceGenome:HGNC:22305
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in testis (RPKM 16.8), heart (RPKM 5.1) and 1 other tissue See more
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    Genomic context

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    See DPY19L2P1 in Genome Data Viewer
    Location:
    7p14.2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (35079989..35186175, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (35221063..35327247, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (35119601..35225787, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102724723 Neighboring gene dpy-19 like C-mannosyltransferase 1 Neighboring gene microRNA 548n Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18092 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:35043370-35043968 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:35067143-35067843 Neighboring gene uncharacterized LOC105375228 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18093 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18094 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25838 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35096856-35097593 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35097594-35098330 Neighboring gene S100A11 pseudogene 2 Neighboring gene VISTA enhancer hs466 Neighboring gene T-box transcription factor 20 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35288961-35289528 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35289529-35290094 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:35292632-35293208 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr7:35296083-35296894 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35296895-35297706 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35297707-35298518 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:35298519-35299329 Neighboring gene uncharacterized LOC401324 Neighboring gene VISTA enhancer hs1659

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation. Virok DP, et al. J Proteome Res, 2011 Apr 1. PMID 21244100
    2. Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease. Teixeira FR, et al. Biochem J, 2016 Oct 15. PMID 27503909, Free PMC Article
    3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. Oláh J, et al. J Biol Chem, 2011 Sep 30. PMID 21832049, Free PMC Article
    4. Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells. Giurato G, et al. Sci Data, 2018 Mar 6. PMID 29509190, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • dpy-19-like 2 pseudogene 1

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002833.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004800, AC005400, AC005826
      Related
      ENST00000458672.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      35079989..35186175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      35221063..35327247 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_026452.1: Suppressed sequence

      Description
      NG_026452.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.

    2. NM_001024657.1: Suppressed sequence

      Description
      NM_001024657.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NXN4.1 GenPept UniProtKB/Swiss-Prot:Q6NXN4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials