U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CCDC158 coiled-coil domain containing 158 [ Homo sapiens (human) ]

    Gene ID: 339965, updated on 19-Sep-2024

    Summary

    Official Symbol
    CCDC158provided by HGNC
    Official Full Name
    coiled-coil domain containing 158provided by HGNC
    Primary source
    HGNC:HGNC:26374
    See related
    Ensembl:ENSG00000163749 AllianceGenome:HGNC:26374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Restricted expression toward testis (RPKM 16.4) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CCDC158 in Genome Data Viewer
    Location:
    4q21.1
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (76313039..76421869, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (79653758..79762651, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (77234192..77342294, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377286 Neighboring gene FAM47E-STBD1 readthrough Neighboring gene family with sequence similarity 47 member E Neighboring gene NFE2L2 motif-containing MPRA enhancer 290 Neighboring gene starch binding domain 1 Neighboring gene RNA, U6 small nuclear 1000, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:77301727-77302231 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:77309531-77310030 Neighboring gene sorting nexin 5 pseudogene 1 Neighboring gene small nucleolar RNA SNORD50 Neighboring gene ribosomal protein L36a pseudogene 18 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:77379997-77381196 Neighboring gene shroom family member 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:77398744-77399474 Neighboring gene RNA, U6 small nuclear 145, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:77479863-77480494 Neighboring gene microRNA 4450

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Phenotypes

    EBI GWAS Catalog

    Description
    New loci associated with kidney function and chronic kidney disease.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ25770, MGC35086

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 158

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042784.1NP_001036249.1  coiled-coil domain-containing protein 158 isoform 2

      See identical proteins and their annotated locations for NP_001036249.1

      Status: VALIDATED

      Source sequence(s)
      BC035224, BC086869
      Consensus CDS
      CCDS43242.1
      UniProtKB/Swiss-Prot
      Q5M9N0, Q8IYQ1, Q8N7D4, Q8N7E3
      Related
      ENSP00000373566.2, ENST00000388914.7
      Conserved Domains (1) summary
      pfam15921
      Location:11113
      CCDC158; Coiled-coil domain-containing protein 158
    2. NM_001394954.1NP_001381883.1  coiled-coil domain-containing protein 158 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC034139, AC096743
      Consensus CDS
      CCDS93551.1
      UniProtKB/TrEMBL
      A0A804HIY6
      Related
      ENSP00000507278.1, ENST00000682701.1
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      76313039..76421869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011531911.2XP_011530213.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530213.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    2. XM_011531917.2XP_011530219.1  coiled-coil domain-containing protein 158 isoform X4

      See identical proteins and their annotated locations for XP_011530219.1

      Conserved Domains (1) summary
      pfam15921
      Location:121035
      CCDC158; Coiled-coil domain-containing protein 158
    3. XM_011531909.3XP_011530211.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530211.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    4. XM_011531912.3XP_011530214.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530214.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    5. XM_011531914.3XP_011530216.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530216.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    6. XM_011531915.3XP_011530217.1  coiled-coil domain-containing protein 158 isoform X3

      Conserved Domains (1) summary
      pfam15921
      Location:11066
      CCDC158; Coiled-coil domain-containing protein 158
    7. XM_005262974.5XP_005263031.1  coiled-coil domain-containing protein 158 isoform X2

      See identical proteins and their annotated locations for XP_005263031.1

      UniProtKB/Swiss-Prot
      Q5M9N0, Q8IYQ1, Q8N7D4, Q8N7E3
      Conserved Domains (1) summary
      pfam15921
      Location:11113
      CCDC158; Coiled-coil domain-containing protein 158
    8. XM_011531908.3XP_011530210.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530210.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    9. XM_017008160.2XP_016863649.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    10. XM_011531910.4XP_011530212.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530212.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158
    11. XM_011531913.1XP_011530215.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_011530215.1

      UniProtKB/TrEMBL
      A0A804HIY6
      Conserved Domains (1) summary
      pfam15921
      Location:11117
      CCDC158; Coiled-coil domain-containing protein 158

    RNA

    1. XR_938729.3 RNA Sequence

    2. XR_938730.3 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      79653758..79762651 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054349915.1XP_054205890.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    2. XM_054349924.1XP_054205899.1  coiled-coil domain-containing protein 158 isoform X4

    3. XM_054349917.1XP_054205892.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    4. XM_054349919.1XP_054205894.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    5. XM_054349921.1XP_054205896.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    6. XM_054349923.1XP_054205898.1  coiled-coil domain-containing protein 158 isoform X3

    7. XM_054349922.1XP_054205897.1  coiled-coil domain-containing protein 158 isoform X2

      UniProtKB/Swiss-Prot
      Q5M9N0, Q8IYQ1, Q8N7D4, Q8N7E3
    8. XM_054349916.1XP_054205891.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    9. XM_054349918.1XP_054205893.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    10. XM_054349914.1XP_054205889.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6
    11. XM_054349920.1XP_054205895.1  coiled-coil domain-containing protein 158 isoform X1

      UniProtKB/TrEMBL
      A0A804HIY6

    RNA

    1. XR_008486975.1 RNA Sequence

    2. XR_008486976.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178555.3: Suppressed sequence

      Description
      NM_178555.3: This RefSeq was permanently suppressed because it has a none consensus splice site that does not have enough supporting evidence.