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    C16orf74 chromosome 16 open reading frame 74 [ Homo sapiens (human) ]

    Gene ID: 404550, updated on 17-Sep-2024

    Summary

    Official Symbol
    C16orf74provided by HGNC
    Official Full Name
    chromosome 16 open reading frame 74provided by HGNC
    Primary source
    HGNC:HGNC:23362
    See related
    Ensembl:ENSG00000154102 AllianceGenome:HGNC:23362
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ASRA
    Expression
    Broad expression in placenta (RPKM 4.1), urinary bladder (RPKM 4.0) and 22 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See C16orf74 in Genome Data Viewer
    Location:
    16q24.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (85707517..85751096, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (91773042..91816616, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (85741123..85784702, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene Gse1 coiled-coil protein Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85721369-85721902 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7817 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7818 Neighboring gene uncharacterized LOC124903740 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85722953-85723454 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85729233-85729805 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85735359-85735574 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85738821-85739513 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85743177-85743746 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85762391-85763258 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11282 Neighboring gene GINS complex subunit 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11283 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11284 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11285 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7819 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7820 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7821 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11286 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11287 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11288 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85808859-85809359 Neighboring gene uncharacterized LOC101928557 Neighboring gene microRNA 1910 Neighboring gene RNA, U1 small nuclear 103, pseudogene Neighboring gene ER membrane protein complex subunit 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein C16orf74
    Names
    adipose-secreted regulator of appetite
    hypothetical protein 1
    hypothetical protein 2
    hypothetical protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_206967.3NP_996850.1  uncharacterized protein C16orf74

      See identical proteins and their annotated locations for NP_996850.1

      Status: VALIDATED

      Source sequence(s)
      AC018695, AW072412, CD674248
      Consensus CDS
      CCDS45540.1
      UniProtKB/Swiss-Prot
      Q96GX8, R4GN89
      UniProtKB/TrEMBL
      A0A0M5MPK6, R4GMY0
      Related
      ENSP00000284245.3, ENST00000284245.9
      Conserved Domains (1) summary
      pfam15366
      Location:1375
      DUF4597; Domain of unknown function (DUF4597)

    RNA

    1. NR_161452.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018695
      Related
      ENST00000602766.1
    2. NR_161453.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018695
      Related
      ENST00000602914.1
    3. NR_161454.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC018695
      Related
      ENST00000602675.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      85707517..85751096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      91773042..91816616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)