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    MIR548G microRNA 548g [ Homo sapiens (human) ]

    Gene ID: 100313938, updated on 17-Sep-2024

    Summary

    Official Symbol
    MIR548Gprovided by HGNC
    Official Full Name
    microRNA 548gprovided by HGNC
    Primary source
    HGNC:HGNC:35326
    See related
    Ensembl:ENSG00000221369 miRBase:MI0006395; AllianceGenome:HGNC:35326
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MIRN548G; hsa-mir-548g
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    Annotation information
    Note: MIR548G (GeneID 100313938) was annotated incorrectly on NCBI's Build 37.2. Its correct location is chr4: 148265781-148265869 (-). [17 Jun 2014]
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    Genomic context

    See MIR548G in Genome Data Viewer
    Location:
    4q31.22
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (147344629..147344717, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (150668794..150668882, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (148265781..148265869, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100996262 Neighboring gene uncharacterized LOC105377476 Neighboring gene NANOG hESC enhancer GRCh37_chr4:148058402-148058938 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:148213466-148214665 Neighboring gene ribosomal protein L31 pseudogene 26 Neighboring gene protein arginine methyltransferase 5 pseudogene 1

    Genomic regions, transcripts, and products

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_031662.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AC010683
      Related
      ENST00000408442.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      147344629..147344717 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      150668794..150668882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)