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    YTA6 putative AAA family ATPase YTA6 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856031, updated on 2-Nov-2024

    Summary

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    Official Symbol
    YTA6
    Official Full Name
    putative AAA family ATPase YTA6
    Primary source
    SGD:S000005995
    Locus tag
    YPL074W
    See related
    AllianceGenome:SGD:S000005995; FungiDB:YPL074W; VEuPathDB:YPL074W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable ATP hydrolysis activity. Involved in positive regulation of translation. Located in cell cortex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 4. Orthologous to human SPAST (spastin). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See YTA6 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (415763..418027)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase Neighboring gene transcription regulator GCR1 Neighboring gene putative ubiquitin-specific protease UBP16 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ASH1 mRNA localization in three acts. Beach DL, et al. Mol Biol Cell, 2001 Sep. PMID 11553699, Free PMC Article
    2. Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex. Schnall R, et al. Yeast, 1994 Sep. PMID 7754704
    3. The evolution of the conserved ATPase domain (CAD): reconstructing the history of an ancient protein module. Swaffield JC, et al. J Mol Evol, 1997 Nov. PMID 9342402
    4. Protein phosphatase type 1 interacts with proteins required for meiosis and other cellular processes in Saccharomyces cerevisiae. Tu J, et al. Mol Cell Biol, 1996 Aug. PMID 8754819, Free PMC Article
    5. Genetic interactions between GLC7, PPZ1 and PPZ2 in saccharomyces cerevisiae. Venturi GM, et al. Genetics, 2000 May. PMID 10790385, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 

    General protein information

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    Preferred Names
    putative AAA family ATPase YTA6
    NP_015251.1
    • Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      415763..418027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183888.1 → NP_015251.1  TPA: putative AAA family ATPase YTA6 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015251.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3U2, P40324, P40328, Q02845, Q05773
      UniProtKB/TrEMBL
      A6ZWH6, B3LKZ6, C7GTY4, N1NVH5
      Conserved Domains (1) summary
      COG0464
      Location:201 → 747
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40328.2

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