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    SLC6A10P solute carrier family 6 member 10, pseudogene [ Homo sapiens (human) ]

    Gene ID: 386757, updated on 17-Sep-2024

    Summary

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    Official Symbol
    SLC6A10Pprovided by HGNC
    Official Full Name
    solute carrier family 6 member 10, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:11043
    See related
    Ensembl:ENSG00000290985 AllianceGenome:HGNC:11043
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT2; CT-2; SLC6A10; SLC6A10pA
    Expression
    Biased expression in testis (RPKM 15.1), adrenal (RPKM 2.0) and 1 other tissue See more
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    Genomic context

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    See SLC6A10P in Genome Data Viewer
    Location:
    16p11.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (32877473..32885142, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (33399529..33407199)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (32888794..32896463, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy variable 2/OR16-5 (non-functional) Neighboring gene B cell receptor associated protein 31 pseudogene 2 Neighboring gene immunoglobulin heavy variable 3/OR16-15 (pseudogene) Neighboring gene immunoglobulin heavy variable 3/OR16-6 (pseudogene)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Assignment of the human creatine transporter type 2 (SLC6A10) to chromosome band 16p11.2 by in situ hybridization. Xu W, et al. Cytogenet Cell Genet, 1997. PMID 9154116
    2. Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolution. Eichler EE, et al. Hum Mol Genet, 1996 Jul. PMID 8817324
    3. Expression profile of COL2A1 and the pseudogene SLC6A10P predicts tumor recurrence in high-grade serous ovarian cancer. Ganapathi MK, et al. Int J Cancer, 2016 Feb 1. PMID 26311224
    4. Cloning and characterization of the promoter regions from the parent and paralogous creatine transporter genes. Ndika JD, et al. Gene, 2014 Jan 10. PMID 24144841
    5. Identification of a testis-expressed creatine transporter gene at 16p11.2 and confirmation of the X-linked locus to Xq28. Iyer GS, et al. Genomics, 1996 May 15. PMID 8661037

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. estimated median of 95 months as compared to an estimated median of 16 months for subjects expressing other levels of COL2A1 and SLC6A10P
      Title: Expression profile of COL2A1 and the pseudogene SLC6A10P predicts tumor recurrence in high-grade serous ovarian cancer.
    2. This is the first experimental evidence of a pseudogene (SLC6A10P) with stronger promoter activity than its parental gene (SLC6A8).
      Title: Cloning and characterization of the promoter regions from the parent and paralogous creatine transporter genes.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • creatine transporter-2
    • solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
    • solute carrier family 6 (neurotransmitter transporter, creatine), member 10, pseudogene

    Clone Names

    • FLJ43855

    General protein information

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    Preferred Names
    similar to sodium- and chloride-dependent creatine transporter

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003083.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC142086
      Related
      ENST00000330048.9

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      32877473..32885142 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      33399529..33407199
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198857.1: Suppressed sequence

      Description
      NM_198857.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.