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    RPL21A ribosomal 60S subunit protein L21A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852489, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPL21A
    Official Full Name
    ribosomal 60S subunit protein L21A
    Primary source
    SGD:S000000395
    Locus tag
    YBR191W
    See related
    AllianceGenome:SGD:S000000395; FungiDB:YBR191W; VEuPathDB:YBR191W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    URP1
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in hypotrichosis 12. Orthologous to human RPL21 (ribosomal protein L21). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL21A in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_001134.8 (606270..607140)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ntc20p Neighboring gene ribosomal 40S subunit protein S9B Neighboring gene Rim2p Neighboring gene Med8p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A 12.5 kb fragment of the yeast chromosome II contains two adjacent genes encoding ribosomal proteins and six putative new genes, one of which encodes a putative transcriptional factor. Démolis N, et al. Yeast, 1994 Nov. PMID 7871891
    2. Yeast single copy gene URP1 is a homolog of rat ribosomal protein gene L21. Jank B, et al. Curr Genet, 1993 Jan. PMID 8428379
    3. Innate immunity to yeast prions: Btn2p and Cur1p curing of the [URE3] prion is prevented by 60S ribosomal protein deficiency or ubiquitin/proteasome system overactivity. Bezsonov EE, et al. Genetics, 2021 Apr 15. PMID 33857305, Free PMC Article
    4. Genome-wide survey of non-essential genes required for slowed DNA synthesis-induced filamentous growth in yeast. Kang CM, et al. Yeast, 2005 Jan 30. PMID 15645503
    5. Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon. Suresh S, et al. Mob DNA, 2015. PMID 26664557, Free PMC Article

    See all (97) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L21A
    NP_009750.1
    • Ribosomal 60S subunit protein L21A; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21A has a paralog, RPL21B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      606270..607140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178539.1 → NP_009750.1  TPA: ribosomal 60S subunit protein L21A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009750.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQI5, Q02753
      UniProtKB/TrEMBL
      A6ZLD1, B3LMX1, D3UET4, G2W9J2, N1P6X8
      Conserved Domains (1) summary
      PTZ00189
      Location:1 → 157
      PTZ00189; 60S ribosomal protein L21; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02753.1

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