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    SNF6 Snf6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856360, updated on 6-Oct-2024

    Summary

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    Official Symbol
    SNF6
    Official Full Name
    Snf6p
    Primary source
    SGD:S000001017
    Locus tag
    YHL025W
    See related
    AllianceGenome:SGD:S000001017; FungiDB:YHL025W; VEuPathDB:YHL025W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables rDNA binding activity. Involved in chromatin remodeling; nucleic acid metabolic process; and positive regulation of transcription, DNA-templated. Located in cytosol and nucleus. Part of SWI/SNF complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SNF6 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (54851..55849)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene alkaline-responsive transcriptional regulator RIM101 Neighboring gene uncharacterized protein Neighboring gene Rim4p Neighboring gene Npr3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Detection of an altered heterochromatin structure in the absence of the nucleotide excision repair protein Rad4 in Saccharomyces cerevisiae. Zhang L, et al. Cell Cycle, 2013 Aug 1. PMID 23839037, Free PMC Article
    2. SNF6 encodes a nuclear protein that is required for expression of many genes in Saccharomyces cerevisiae. Estruch F, et al. Mol Cell Biol, 1990 Jun. PMID 2188093, Free PMC Article
    3. The SNF2, SNF5 and SNF6 genes are required for Ty transcription in Saccharomyces cerevisiae. Happel AM, et al. Genetics, 1991 May. PMID 1648006, Free PMC Article
    4. SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes. Nikolov VN, et al. Nat Commun, 2022 Apr 12. PMID 35413952, Free PMC Article
    5. Assays for chromatin remodeling during nucleotide excision repair in Saccharomyces cerevisiae. Zhang L, et al. Methods, 2009 May. PMID 19336254, Free PMC Article

    See all (140) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structure of the yeast Swi/Snf complex in a nucleosome free state.
      Title: Structure of the yeast Swi/Snf complex in a nucleosome free state.
    2. These results indicate that the SWI/SNF chromatin-remodeling complex is recruited to DNA lesions by damage-recognition proteins to increase DNA accessibility for NER in chromatin.
      Title: Rad4-Rad23 interaction with SWI/SNF links ATP-dependent chromatin remodeling with nucleotide excision repair.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rDNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maturation of LSU-rRNA IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleotide-excision repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleotide-excision repair IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SWI/SNF complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Snf6p
    NP_011838.1
    • Subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; relocates to the cytosol under hypoxic conditions

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      54851..55849
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179105.1 → NP_011838.1  TPA: Snf6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011838.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKU3, P18888
      UniProtKB/TrEMBL
      A6ZSM6, B3LS94, C7GIR1, C8ZA39, G2WF41, N1P160
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P18888.1

    Gene LinkOut

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