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    RPS1A ribosomal 40S subunit protein S1A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851162, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPS1A
    Official Full Name
    ribosomal 40S subunit protein S1A
    Primary source
    SGD:S000004433
    Locus tag
    YLR441C
    See related
    AllianceGenome:SGD:S000004433; FungiDB:YLR441C; VEuPathDB:YLR441C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RP10A
    Summary
    Predicted to be a structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of 90S preribosome. Orthologous to human RPS3A (ribosomal protein S3A). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPS1A in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (1018141..1018908, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL4 Neighboring gene Sec39p Neighboring gene chromatin-silencing protein SIR3 Neighboring gene Ecm7p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and regulation of a Candida albicans RP10 gene which encodes an immunogenic protein homologous to Saccharomyces cerevisiae ribosomal protein 10. Swoboda RK, et al. J Bacteriol, 1995 Mar. PMID 7868597, Free PMC Article
    2. A gene family homologous to the S-phase specific gene in higher plants is essential for cell proliferation in Saccharomyces cerevisiae. Ito M, et al. FEBS Lett, 1992 Apr 13. PMID 1451783
    3. Structure of the 80S ribosome-Xrn1 nuclease complex. Tesina P, et al. Nat Struct Mol Biol, 2019 Apr. PMID 30911188
    4. The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. Schopf FH, et al. Mol Cell, 2019 Apr 4. PMID 30876805
    5. Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast. Moteshareie H, et al. PLoS One, 2018. PMID 30231023, Free PMC Article

    See all (107) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study reports on the finding of two genes, ITT1, an inhibitor of translation termination, and RPS1A, a small ribosomal protein, that when deleted yeast cells exhibit similar metal sensitivity phenotypes to gene deletion strain for URE2.
      Title: Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S1A
    NP_013546.1
    • Ribosomal protein of the small (40S) subunit; homologous to mammalian ribosomal protein S3A, no bacterial homolog; RPS1A has a paralog, RPS1B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      1018141..1018908 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182329.1 → NP_013546.1  TPA: ribosomal 40S subunit protein S1A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013546.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7A1W1, B3RHV0, B5VNY0, C7GSL4, D6VZ76, P33442
      UniProtKB/TrEMBL
      G2WJQ2, N1P1Y6
      Conserved Domains (1) summary
      pfam01015
      Location:15 → 221
      Ribosomal_S3Ae; Ribosomal S3Ae family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P33442.2

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