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    YIF1 protein transporter YIF1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855458, updated on 18-Sep-2024

    Summary

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    Official Symbol
    YIF1
    Official Full Name
    protein transporter YIF1
    Primary source
    SGD:S000005207
    Locus tag
    YNL263C
    See related
    AllianceGenome:SGD:S000005207; FungiDB:YNL263C; VEuPathDB:YNL263C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in COPII-coated ER to Golgi transport vesicle and endoplasmic reticulum membrane. Is integral component of Golgi membrane. Orthologous to human YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein) and YIF1B (Yip1 interacting factor homolog B, membrane trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See YIF1 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (146896..147840, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Ist1p Neighboring gene phosphatidylinositol transporter Neighboring gene DNA polymerase epsilon catalytic subunit Neighboring gene origin recognition complex subunit 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex. Heidtman M, et al. Mol Biol Cell, 2005 Apr. PMID 15659647, Free PMC Article
    2. The yeast model for Batten disease: a role for Btn2p in the trafficking of the Golgi-associated vesicular targeting protein, Yif1p. Chattopadhyay S, et al. Biochem Biophys Res Commun, 2003 Mar 14. PMID 12615067
    3. The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. Barrowman J, et al. J Biol Chem, 2003 May 30. PMID 12657649
    4. Perinuclear localization of chromatin facilitates transcriptional silencing. Andrulis ED, et al. Nature, 1998 Aug 6. PMID 9707122
    5. Multicopy suppressor analysis of thermosensitive YIP1 alleles implicates GOT1 in transport from the ER. Lorente-Rodríguez A, et al. J Cell Sci, 2009 May 15. PMID 19383723, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Yos1p associates with Yip1p and Yif1p, indicating Yos1p is a novel subunit of the Yip1p-Yif1p complex
      Title: Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in COPII-coated ER to Golgi transport vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in COPII-coated ER to Golgi transport vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein transporter YIF1
    NP_014136.1
    • Integral membrane protein; required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      146896..147840 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183101.1 → NP_014136.1  TPA: protein transporter YIF1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014136.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0T0, P53845
      UniProtKB/TrEMBL
      A6ZRI0, B5VQE9, C7GP99, C8ZFX6, G2WLK2, N1NWY4
      Conserved Domains (1) summary
      COG5197
      Location:22 → 314
      COG5197; Predicted membrane protein [Function unknown]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53845.1

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