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    RPC82 DNA-directed RNA polymerase III subunit C82 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856320, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPC82
    Official Full Name
    DNA-directed RNA polymerase III subunit C82
    Primary source
    SGD:S000006394
    Locus tag
    YPR190C
    See related
    AllianceGenome:SGD:S000006394; FungiDB:YPR190C; VEuPathDB:YPR190C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPC3; RPC80
    Summary
    Contributes to RNA polymerase III activity. Involved in tRNA transcription by RNA polymerase III. Part of RNA polymerase III complex. Orthologous to human POLR3C (RNA polymerase III subunit C). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPC82 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (917077..919041, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mlc2p Neighboring gene SKI complex subunit tetratricopeptide repeat protein SKI3 Neighboring gene ubiquinol--cytochrome-c reductase subunit 2 Neighboring gene Aqy1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression. Roberts DN, et al. Mol Cell, 2006 Jun 9. PMID 16762836, Free PMC Article
    2. RPC82 encodes the highly conserved, third-largest subunit of RNA polymerase C (III) from Saccharomyces cerevisiae. Chiannilkulchai N, et al. Mol Cell Biol, 1992 Oct. PMID 1406632, Free PMC Article
    3. Dual role of the C34 subunit of RNA polymerase III in transcription initiation. Brun I, et al. EMBO J, 1997 Sep 15. PMID 9312031, Free PMC Article
    4. Two steps in Maf1-dependent repression of transcription by RNA polymerase III. Desai N, et al. J Biol Chem, 2005 Feb 25. PMID 15590667
    5. Inhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic Acid. Jurkiewicz A, et al. Mol Cell Biol, 2019 Dec 11. PMID 31658995, Free PMC Article

    See all (63) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase III activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA transcription by RNA polymerase III IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in tRNA transcription by RNA polymerase III IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase III complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase III complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase III subunit C82
    NP_015516.1
    • RNA polymerase III subunit C82

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      917077..919041 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184287.1 → NP_015516.1  TPA: DNA-directed RNA polymerase III subunit C82 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015516.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZX64, D6W4J0, P32349, Q06591
      UniProtKB/TrEMBL
      B3LKE9, B5VTW9, C7GP71, C8ZJL9, N1NWL2
      Conserved Domains (2) summary
      pfam05645
      Location:189 → 487
      RNA_pol_Rpc82; RNA polymerase III subunit RPC82
      pfam08221
      Location:47 → 109
      HTH_9; RNA polymerase III subunit RPC82 helix-turn-helix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32349.2

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