Rabl6 RAB, member RAS oncogene family-like 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rabl6provided by RGD
Official Full Name: RAB, member RAS oncogene family-like 6provided by RGD
Primary source: RGD:1307615
See related: EnsemblRapid:ENSRNOG00000016795 AllianceGenome:RGD:1307615
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1307615
Summary: Predicted to enable GTP binding activity. Predicted to be located in centrosome and cytoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human RABL6 (RAB, member RAS oncogene family like 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 229.3), Muscle (RPKM 189.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3p13

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (28800802..28826722, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (8402666..8428588, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (2806777..2832697, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: rab-like protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108573.1 → NP_001102043.1 rab-like protein 6

See identical proteins and their annotated locations for NP_001102043.1

Status: PROVISIONAL

Source sequence(s)

CH474001

UniProtKB/TrEMBL

A6JT87, D3ZKQ4

Related

ENSRNOP00000060618.2, ENSRNOT00000065410.3

Conserved Domains (2) summary

pfam00071
Location:45 → 221

Ras; Ras family

cl21455
Location:44 → 221

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

28800802..28826722 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039105351.2 → XP_038961279.1 rab-like protein 6 isoform X1

Conserved Domains (3) summary

PRK04654
Location:107 → 266

PRK04654; sec-independent translocase; Provisional

PHA03307
Location:177 → 423

PHA03307; transcriptional regulator ICP4; Provisional

cl38936
Location:11 → 95

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
XM_039105353.2 → XP_038961281.1 rab-like protein 6 isoform X2

Conserved Domains (1) summary

PRK14951
Location:75 → 189

PRK14951; DNA polymerase III subunits gamma and tau; Provisional