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    Ptov1 PTOV1, extended AT-hook containing adaptor protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292888, updated on 2-Nov-2024

    Summary

    Official Symbol
    Ptov1provided by RGD
    Official Full Name
    PTOV1, extended AT-hook containing adaptor proteinprovided by RGD
    Primary source
    RGD:1306977
    See related
    EnsemblRapid:ENSRNOG00000020358 AllianceGenome:RGD:1306977
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Orthologous to human PTOV1 (PTOV1 extended AT-hook containing adaptor protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 219.2), Adrenal (RPKM 203.8) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ptov1 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (104483553..104496161, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (95347065..95354514, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (100859346..100866917, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene AKT1 substrate 1 Neighboring gene polynucleotide kinase 3'-phosphatase Neighboring gene mediator complex subunit 25 Neighboring gene fuzzy planar cell polarity protein Neighboring gene adaptor related protein complex 2 subunit alpha 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC94482

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    prostate tumor-overexpressed gene 1 protein homolog
    Names
    prostate tumor over expressed gene 1
    prostate tumor overexpressed 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008304.1NP_001008305.1  prostate tumor-overexpressed gene 1 protein homolog

      See identical proteins and their annotated locations for NP_001008305.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085836
      UniProtKB/Swiss-Prot
      Q5U2W6
      UniProtKB/TrEMBL
      A6JAT8
      Related
      ENSRNOP00000027580.3, ENSRNOT00000027580.6
      Conserved Domains (1) summary
      pfam11232
      Location:93238
      Med25; Mediator complex subunit 25 PTOV activation and synapsin 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      104483553..104496161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_350313.5 RNA Sequence