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    FAT3 Fat3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853648, updated on 3-Nov-2024

    Summary

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    Official Symbol
    FAT3
    Official Full Name
    Fat3p
    Primary source
    SGD:S000001670
    Locus tag
    YKL187C
    See related
    AllianceGenome:SGD:S000001670; FungiDB:YKL187C; VEuPathDB:YKL187C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in long-chain fatty acid transport. Located in cell periphery and mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See FAT3 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (89284..91536, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Hym1p Neighboring gene ATP-binding cassette long-chain fatty acid transporter PXA2 Neighboring gene Mtr2p Neighboring gene DNA-binding transcription repressor ASH1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Global analysis of condition-specific subcellular protein distribution and abundance. Jung S, et al. Mol Cell Proteomics, 2013 May. PMID 23349476, Free PMC Article
    2. Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Reinders J, et al. Mol Cell Proteomics, 2007 Nov. PMID 17761666
    3. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
    4. Exploring the yeast acetylome using functional genomics. Kaluarachchi Duffy S, et al. Cell, 2012 May 11. PMID 22579291, Free PMC Article
    5. Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis. Corcoles-Saez I, et al. Dev Cell, 2018 Aug 20. PMID 30130531

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in long-chain fatty acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell cortex of cell tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell periphery HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fat3p
    NP_012734.1
    • Protein required for fatty acid uptake; protein abundance increases in cortical patches in response to oleate exposure; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; FAT3 has a paralog, YLR413W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      89284..91536 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179753.1 → NP_012734.1  TPA: Fat3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012734.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX13, P34231
      UniProtKB/TrEMBL
      B5VLX5, C8ZBY9, N1P0M4
      Conserved Domains (1) summary
      cl02193
      Location:210 → 362
      VirB5_like; VirB5 protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34231.1

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