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    RAD33 Rad33p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854998, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAD33
    Official Full Name
    Rad33p
    Primary source
    SGD:S000004472
    Locus tag
    YML011C
    See related
    AllianceGenome:SGD:S000004472; FungiDB:YML011C; VEuPathDB:YML011C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in nucleotide-excision repair. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RAD33 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (246895..247428, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Ubx2p Neighboring gene Erv25p Neighboring gene transcription elongation factor SPT5 Neighboring gene mitochondrial 54S ribosomal protein YmL39

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Architecture of the human XPC DNA repair and stem cell coactivator complex. Zhang ET, et al. Proc Natl Acad Sci U S A, 2015 Dec 1. PMID 26627236, Free PMC Article
    2. Rad33, a new factor involved in nucleotide excision repair in Saccharomyces cerevisiae. den Dulk B, et al. DNA Repair (Amst), 2006 Jun 10. PMID 16595192
    3. Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair. van Eeuwen T, et al. Nat Commun, 2021 Jun 7. PMID 34099686, Free PMC Article
    4. The NER protein Rad33 shows functional homology to human Centrin2 and is involved in modification of Rad4. den Dulk B, et al. DNA Repair (Amst), 2008 Jun 1. PMID 18387345
    5. Previously uncharacterized genes in the UV- and MMS-induced DNA damage response in yeast. Hanway D, et al. Proc Natl Acad Sci U S A, 2002 Aug 6. PMID 12149442, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleotide-excision repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rad33p
    NP_013702.1
    • Protein involved in nucleotide excision repair; green fluorescent protein (GFP)-fusion protein localizes to the nucleus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      246895..247428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182368.1 → NP_013702.1  TPA: Rad33p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013702.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZG3, Q04231
      UniProtKB/TrEMBL
      A6ZM51, B3LLP0, B5VPB6, C7GLC9, C8ZEJ4, G2WK41, N1P038
      Conserved Domains (1) summary
      pfam08730
      Location:18 → 141
      Rad33
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04231.1

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