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    isu1 Fe-sulfur cluster assembly protein Isu1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541513, updated on 17-Aug-2024

    Summary

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    Gene symbol
    isu1
    Gene description
    Fe-sulfur cluster assembly protein Isu1
    Primary source
    PomBase:SPAC227.13c
    Locus tag
    SPOM_SPAC227.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See isu1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (517416..518951, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene folylpolyglutamate synthase Neighboring gene prefoldin subunit 2 Neighboring gene putative misfolded glycoprotein sensor Yos9 Neighboring gene Prp4 family U4/U5/U6 small nuclear ribonucleoprotein complex subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uridine kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. Wu G, et al. Biochemistry, 2002 Apr 16. PMID 11939799
    2. Iron-sulfur cluster biosynthesis. Kinetic analysis of [2Fe-2S] cluster transfer from holo ISU to apo Fd: role of redox chemistry and a conserved aspartate. Wu SP, et al. Biochemistry, 2002 Jul 16. PMID 12102630
    3. Iron-Sulfur Cluster Biogenesis Chaperones: Evidence for Emergence of Mutational Robustness of a Highly Specific Protein-Protein Interaction. Delewski W, et al. Mol Biol Evol, 2016 Mar. PMID 26545917, Free PMC Article
    4. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 2 iron, 2 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ferrous iron binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron-sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables iron-sulfur cluster carrier activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in [2Fe-2S] cluster assembly EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in [2Fe-2S] cluster assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in intracellular iron ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in iron-sulfur cluster assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Fe-sulfur cluster assembly protein Isu1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      517416..518951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018367.3 → NP_592967.1  Fe-sulfur cluster assembly protein Isu1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592967.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTC6
      Conserved Domains (1) summary
      TIGR01999
      Location:54 → 177
      iscU; FeS cluster assembly scaffold IscU
    Nucleotide Protein
    Heading Accession and Version

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