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    ppc89 protein Ppc89 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543554, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ppc89
    Official Full Name
    protein Ppc89
    Primary source
    PomBase:SPAC4H3.11c
    Locus tag
    SPOM_SPAC4H3.11C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mug127
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    Genomic context

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    See ppc89 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3847958..3850740, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pyruvate kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface. Chen JS, et al. Mol Biol Cell, 2024 Aug 1. PMID 38985524, Free PMC Article
    2. The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole. Elmore ZC, et al. Mol Biol Cell, 2018 Jul 1. PMID 29742018, Free PMC Article
    3. Ppc89 links multiple proteins, including the septation initiation network, to the core of the fission yeast spindle-pole body. Rosenberg JA, et al. Mol Biol Cell, 2006 Sep. PMID 16775007, Free PMC Article
    4. Dialogue between centrosomal entrance and exit scaffold pathways regulates mitotic commitment. Chan KY, et al. J Cell Biol, 2017 Sep 4. PMID 28774892, Free PMC Article
    5. Molecular model of fission yeast centrosome assembly determined by superresolution imaging. Bestul AJ, et al. J Cell Biol, 2017 Aug 7. PMID 28619713, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface.
      Title: The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables spindle pole body anchor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic spindle organization EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in central plaque of mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Ppc89

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3847958..3850740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019768.3 → NP_594347.1  protein Ppc89 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594347.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10218
      Conserved Domains (2) summary
      pfam06657
      Location:701 → 775
      Cep57_MT_bd; Centrosome microtubule-binding domain of Cep57
      pfam14197
      Location:365 → 433
      Cep57_CLD_2; Centrosome localization domain of PPC89
    Nucleotide Protein
    Heading Accession and Version

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