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    pgl1 6-phosphogluconolactonase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538922, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pgl1
    Official Full Name
    6-phosphogluconolactonase
    Primary source
    PomBase:SPCC16C4.10
    Locus tag
    SPOM_SPCC16C4.10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See pgl1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (685879..687406)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Dis3L2-like 3'-5'-exoribonuclease Neighboring gene ncRNA Neighboring gene DNA polymerase epsilon Dpb3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cyclin-dependent protein kinase Pho85/PhoA-like Pef1 Neighboring gene NatB N-acetyltransferase complex catalytic subunit Naa20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Repression of enzymes of the pentose phosphate pathway by glucose in fission yeast. Mehta S, et al. FEBS Lett, 1998 Dec 4. PMID 9872416
    2. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 6-phosphogluconolactonase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables 6-phosphogluconolactonase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in pentose-phosphate shunt, oxidative branch EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt, oxidative branch IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    6-phosphogluconolactonase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      685879..687406
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022911.3 → NP_587920.1  6-phosphogluconolactonase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587920.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74455
      Conserved Domains (1) summary
      cd01400
      Location:12 → 239
      6PGL; 6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard ...
    Nucleotide Protein
    Heading Accession and Version

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