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    tRNA (guanine(26)-N(2))-dimethyltransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831438, updated on 18-Sep-2024

    Summary

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    Official Full Name
    tRNA (guanine(26)-N(2))-dimethyltransferase
    Primary source
    TAIR:AT5G15810
    Locus tag
    AT5G15810
    See related
    Araport:AT5G15810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14F8.190; F14F8_190
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (5157841..5161363)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene chaperone Neighboring gene tRNA-Ile Neighboring gene tRNA-Asp Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the enzymes responsible for m2,2G and acp3U formation on cytosolic tRNA from insects and plants. Funk HM, et al. PLoS One, 2020. PMID 33253256, Free PMC Article
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_121586.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables tRNA (guanine(10)-N2)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (guanine(26)-N2)-dimethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA modification IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    tRNA (guanine(26)-N(2))-dimethyltransferase
    NP_197085.3
    • N2,N2-dimethylguanosine tRNA methyltransferase; FUNCTIONS IN: RNA binding, tRNA (guanine-N2-)-methyltransferase activity; INVOLVED IN: tRNA processing; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: N2,N2-dimethylguanosine tRNA methyltransferase (InterPro:IPR002905); BEST Arabidopsis thaliana protein match is: N2,N2-dimethylguanosine tRNA methyltransferase (TAIR:AT3G02320.1); Has 1017 Blast hits to 963 proteins in 359 species: Archae - 255; Bacteria - 70; Metazoa - 198; Fungi - 150; Plants - 103; Viruses - 0; Other Eukaryotes - 241 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5157841..5161363
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121586.3 → NP_197085.3  tRNA (guanine(26)-N(2))-dimethyltransferase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KB92, Q8RXS4, Q9LFU5
      UniProtKB/TrEMBL
      A0A5S9Y563, A0A654G221
      Conserved Domains (1) summary
      cl17173
      Location:10 → 466
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFU5.3

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