AT5G22400 Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: AT5G22400
Gene description: Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein
Primary source: Araport:AT5G22400
Locus tag: AT5G22400
See related: TAIR:AT5G22400
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MWD9.20; MWD9_20
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Genomic context

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See AT5G22400 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 5

Sequence:: Chromosome: 5; NC_003076.8 (7422670..7425574, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis Atropgap1 and Atropgap4 knockout mutants display enhanced susceptibility to the powdery mildew fungus Erysiphe cruciferarum. [ROPGAP1]
Title: ROPGAPs of Arabidopsis limit susceptibility to powdery mildew.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_122145.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein

NP_197632.1

Rho GTPase activating protein with PAK-box/P21-Rho-binding domain; FUNCTIONS IN: Rac GTPase activator activity; INVOLVED IN: signal transduction; LOCATED IN: intracellular, chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: PAK-box/P21-Rho-binding (InterPro:IPR000095), Rho GTPase activation protein (InterPro:IPR008936), RhoGAP (InterPro:IPR000198); BEST Arabidopsis thaliana protein match is: rac GTPase activating protein (TAIR:AT3G11490.1); Has 3977 Blast hits to 3976 proteins in 184 species: Archae - 0; Bacteria - 0; Metazoa - 2927; Fungi - 443; Plants - 206; Viruses - 0; Other Eukaryotes - 401 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

7422670..7425574 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_122145.5 → NP_197632.1 Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_197632.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FMR1

UniProtKB/TrEMBL

A0A178UPX4

Conserved Domains (2) summary

smart00324
Location:178 → 337

RhoGAP; GTPase-activator protein for Rho-like GTPases

cd00132
Location:115 → 155

CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...