U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    WNK6 with no lysine (K) kinase 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821406, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    WNK6
    Official Full Name
    with no lysine (K) kinase 6
    Primary source
    TAIR:AT3G18750
    Locus tag
    AT3G18750
    See related
    Araport:AT3G18750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA WITH NO K 6; ATWNK6; with no lysine (K) kinase 6; ZIK5
    Summary
    Encodes a member of the WNK family (9 members in all) of protein kinases, the structural design of which is clearly distinct from those of other known protein kinases, such as receptor-like kinases and mitogen-activated protein kinases. Its transcription is under the control of circadian rhythms.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See WNK6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (6454013..6457613, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene tetratricopeptide repeat (TPR)-containing protein Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein Neighboring gene Translation elongation factor EF1B/ribosomal protein S6 family protein Neighboring gene Autophagy-related protein 13

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms. Nakamichi N, et al. Biosci Biotechnol Biochem, 2002 Nov. PMID 12506983
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help
    NM_001035646.2
    NM_001202999.2
    NM_001338354.1
    NM_001338355.1
    NM_001338356.1
    NM_112761.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein phosphorylation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    with no lysine (K) kinase 6
    NP_001189928.1
    • with no lysine (K) kinase 6 (WNK6); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G49160.2).
    NP_001319584.1
    • with no lysine (K) kinase 6 (WNK6); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G49160.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_188505.1
    • with no lysine (K) kinase 6 (WNK6); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G49160.2); Has 109997 Blast hits to 108787 proteins in 3825 species: Archae - 81; Bacteria - 10561; Metazoa - 41131; Fungi - 10681; Plants - 29357; Viruses - 431; Other Eukaryotes - 17755 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6454013..6457613 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202999.2 → NP_001189928.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189928.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V3U7, Q8S8Y8, Q9LSA2
      UniProtKB/TrEMBL
      A0A178V4R3
      Conserved Domains (2) summary
      smart00220
      Location:32 → 285
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd13983
      Location:26 → 285
      STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase

    2. NM_001338355.1 → NP_001326381.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V4R3, A0A1I9LP39

    3. NM_001035646.2 → NP_001030723.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030723.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V4R3
      Conserved Domains (2) summary
      smart00220
      Location:32 → 183
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:26 → 218
      PKc_like; Protein Kinases, catalytic domain

    4. NM_001338354.1 → NP_001319584.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V4R3

    5. NM_001338356.1 → NP_001326380.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V3U7, Q8S8Y8, Q9LSA2
      UniProtKB/TrEMBL
      A0A178V4R3

    6. NM_112761.3 → NP_188505.1  with no lysine (K) kinase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188505.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V3U7, Q8S8Y8, Q9LSA2
      UniProtKB/TrEMBL
      A0A178V4R3
      Conserved Domains (2) summary
      smart00220
      Location:32 → 285
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd13983
      Location:26 → 285
      STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8S8Y8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.