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    TIM23-2 translocase inner membrane subunit 23-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843607, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIM23-2
    Official Full Name
    translocase inner membrane subunit 23-2
    Primary source
    TAIR:AT1G72750
    Locus tag
    AT1G72750
    See related
    Araport:AT1G72750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTIM23-2; translocase inner membrane subunit 23-2
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    Genomic context

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    See TIM23-2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (27383320..27384524)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Homeodomain-like/winged-helix DNA-binding family protein Neighboring gene uncharacterized protein Neighboring gene Protein kinase superfamily protein Neighboring gene HYPERSENSITIVE TO ABA1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual location of the mitochondrial preprotein transporters B14.7 and Tim23-2 in complex I and the TIM17:23 complex in Arabidopsis links mitochondrial activity and biogenesis. Wang Y, et al. Plant Cell, 2012 Jun. PMID 22730406, Free PMC Article
    2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    3. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. B14.7 and Tim23-2 are present in respiratory chain complex I
      Title: Dual location of the mitochondrial preprotein transporters B14.7 and Tim23-2 in complex I and the TIM17:23 complex in Arabidopsis links mitochondrial activity and biogenesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105934.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of TIM23 mitochondrial import inner membrane translocase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    translocase inner membrane subunit 23-2
    NP_177419.1
    • translocase inner membrane subunit 23-2 (TIM23-2); FUNCTIONS IN: protein transporter activity, P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: intracellular protein transport, protein transport; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, subunit Tim23 (InterPro:IPR005681), Mitochondrial inner membrane translocase complex, subunit Tim17/22 (InterPro:IPR003397); BEST Arabidopsis thaliana protein match is: translocase of inner mitochondrial membrane 23 (TAIR:AT1G17530.1); Has 613 Blast hits to 613 proteins in 178 species: Archae - 0; Bacteria - 0; Metazoa - 286; Fungi - 136; Plants - 143; Viruses - 0; Other Eukaryotes - 48 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27383320..27384524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105934.2 → NP_177419.1  translocase inner membrane subunit 23-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177419.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38820
      UniProtKB/TrEMBL
      A0A178W370, A0A5S9WTU1, A0A654EQ41
      Conserved Domains (1) summary
      cl02381
      Location:34 → 160
      Tim17; Tim17/Tim22/Tim23/Pmp24 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38820.1

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