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    LSM8 Small nuclear ribonucleoprotein family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842881, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LSM8
    Official Full Name
    Small nuclear ribonucleoprotein family protein
    Primary source
    TAIR:AT1G65700
    Locus tag
    AT1G65700
    See related
    Araport:AT1G65700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtLSM8; F1E22.8; F1E22_8; SM-like 8
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    Genomic context

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    See LSM8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (24434203..24436456, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene beta expansin 6 Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene serine/arginine repetitive matrix-like protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Environment-dependent regulation of spliceosome activity by the LSM2-8 complex in Arabidopsis. Carrasco-López C, et al. Nucleic Acids Res, 2017 Jul 7. PMID 28482101, Free PMC Article
    2. LSM proteins provide accurate splicing and decay of selected transcripts to ensure normal Arabidopsis development. Perea-Resa C, et al. Plant Cell, 2012 Dec. PMID 23221597, Free PMC Article
    3. Prefoldins contribute to maintaining the levels of the spliceosome LSM2-8 complex through Hsp90 in Arabidopsis. Esteve-Bruna D, et al. Nucleic Acids Res, 2020 Jun 19. PMID 32396196, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Environment-dependent regulation of spliceosome activity by the LSM8 isoforms in Arabidopsis has been demonstrated.
      Title: Environment-dependent regulation of spliceosome activity by the LSM2-8 complex in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036161.1
    NM_001198394.1
    NM_105244.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Small nuclear ribonucleoprotein family protein
    NP_001031238.1
    • Small nuclear ribonucleoprotein family protein; CONTAINS InterPro DOMAIN/s: Like-Sm ribonucleoprotein (LSM) domain (InterPro:IPR001163), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro:IPR006649), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro:IPR010920); BEST Arabidopsis thaliana protein match is: Small nuclear ribonucleoprotein family protein (TAIR:AT1G19120.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001185323.1
    • Small nuclear ribonucleoprotein family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus, small nucleolar ribonucleoprotein complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Like-Sm ribonucleoprotein (LSM) domain (InterPro:IPR001163), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro:IPR010920), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro:IPR006649).
    NP_176747.1
    • Small nuclear ribonucleoprotein family protein; CONTAINS InterPro DOMAIN/s: Like-Sm ribonucleoprotein (LSM) domain (InterPro:IPR001163), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro:IPR006649), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro:IPR010920); BEST Arabidopsis thaliana protein match is: Small nuclear ribonucleoprotein family protein (TAIR:AT1G19120.1); Has 967 Blast hits to 967 proteins in 213 species: Archae - 2; Bacteria - 0; Metazoa - 384; Fungi - 316; Plants - 144; Viruses - 0; Other Eukaryotes - 121 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24434203..24436456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198394.1 → NP_001185323.1  Small nuclear ribonucleoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185323.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IBJ7
      Conserved Domains (1) summary
      cd01727
      Location:7 → 137
      LSm8; Like-Sm protein 8

    2. NM_105244.4 → NP_176747.1  Small nuclear ribonucleoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176747.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VYI0, Q9SHY4
      UniProtKB/TrEMBL
      A0A178W8C1, A0A5S9WQ38
      Conserved Domains (1) summary
      cd01727
      Location:7 → 94
      LSm8; Like-Sm protein 8

    3. NM_001036161.1 → NP_001031238.1  Small nuclear ribonucleoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031238.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VYI0, Q9SHY4
      UniProtKB/TrEMBL
      A0A178W8C1, A0A5S9WQ38
      Conserved Domains (1) summary
      cd01727
      Location:7 → 94
      LSm8; Like-Sm protein 8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VYI0.1

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