TCP1 TCP family transcription factor [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: TCP1
Official Full Name: TCP family transcription factor
Primary source: TAIR:AT1G67260
Locus tag: AT1G67260
See related: Araport:AT1G67260
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F1N21.8
Summary: Encodes protein with TCP (TB1,CYC,PCF) domain which is likely to be involved in DNA binding and protein-protein interactions. Based on genome analysis, there is a 9-member gene family that possesses this domain in Arabidopsis. Orthologue of Antirrhinum gene CYCLOIDEA.
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Genomic context

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See TCP1 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 3

Sequence:: Chromosome: 1; NC_003070.9 (25167418..25169707, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Voltage-gating and cytosolic Ca(2+) activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Title: Voltage-gating and cytosolic Ca(2+) activation mechanisms of Arabidopsis two-pore channel AtTPC1.
TB/CYC (TEOSINTE-BRANCHED/CYCLOIDEA)-TCP1 & TCP2 are destabilized by phytoplasma SAP11 effectors, leading to the proliferation of axillary meristems.
Title: Alterations of plant architecture and phase transition by the phytoplasma virulence factor SAP11.
TCP1 Modulates DWF4 Expression via Directly Interacting with the GGNCCC Motifs in the Promoter Region of DWF4 in Arabidopsis thaliana
Title: TCP1 Modulates DWF4 Expression via Directly Interacting with the GGNCCC Motifs in the Promoter Region of DWF4 in Arabidopsis thaliana.
Data indicate that transcription factors TCP-NGA regulatory interaction is likely conserved in angiosperms, including important crop species.
Title: Leaf expansion in Arabidopsis is controlled by a TCP-NGA regulatory module likely conserved in distantly related species.
TCP1 positively regulates BR biosynthesis via its direct regulation of the transcription of DWF4.
Title: TCP1 positively regulates the expression of DWF4 in Arabidopsis thaliana.
important roles of Arabidopsis TCP1 in the longitudinal elongation of petioles, rosette leaves and inflorescent stems
Title: A role of TCP1 in the longitudinal elongation of leaves in Arabidopsis.
TCP1 positively regulates the expression of the key brassinosteroid biosynthetic gene, DWF4.
Title: TCP1 modulates brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001084312.1

Supported by ESTs:

NM_001160982.2

Supported by ESTs:

NM_001334285.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within flower development	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: TCP family transcription factor

NP_001077781.1

TCP1; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), CYC/TB1, R domain (InterPro:IPR017888), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP domain protein 12 (TAIR:AT1G68800.1); Has 1624 Blast hits to 1624 proteins in 376 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 1618; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

NP_001154454.1

TCP1; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: flower development; LOCATED IN: cellular_component unknown; EXPRESSED IN: floral meristem; EXPRESSED DURING: 1 floral meristem visible, 2 floral meristem notched; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), CYC/TB1, R domain (InterPro:IPR017888), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP domain protein 12 (TAIR:AT1G68800.1); Has 1627 Blast hits to 1627 proteins in 374 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 1623; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).