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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001256725.2 → NP_001243654.1 ubiquitin carboxyl-terminal hydrolase 39 isoform 1
See identical proteins and their annotated locations for NP_001243654.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the 3' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (1).
- Source sequence(s)
-
AI201523, BC067273
- Consensus CDS
-
CCDS33234.1
- UniProtKB/Swiss-Prot
- A8K086, B3KM40, B4DHT4, D6W5L4, G5E9H0, Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310
- UniProtKB/TrEMBL
-
B9A018
- Related
- ENSP00000386864.1, ENST00000409470.5
- Conserved Domains (1) summary
-
- cd02669
Location:106 → 553
- Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
-
NM_001256726.2 → NP_001243655.1 ubiquitin carboxyl-terminal hydrolase 39 isoform 2
See identical proteins and their annotated locations for NP_001243655.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AI201523, AK001047, AL519827, DB124294
- Consensus CDS
-
CCDS58717.1
- UniProtKB/TrEMBL
-
B9A018
- Related
- ENSP00000386803.3, ENST00000409766.7
- Conserved Domains (2) summary
-
- cd02669
Location:106 → 477
- Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam00443
Location:224 → 476
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
NM_001256727.2 → NP_001243656.1 ubiquitin carboxyl-terminal hydrolase 39 isoform 3
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK001772, AK302236, BC001384, DB444135
- Consensus CDS
-
CCDS74534.1
- UniProtKB/TrEMBL
- A0A087X1B2, B7Z7L9
- Related
- ENSP00000484024.1, ENST00000613444.4
- Conserved Domains (1) summary
-
- cd02669
Location:28 → 475
- Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
-
NM_001256728.2 → NP_001243657.1 ubiquitin carboxyl-terminal hydrolase 39 isoform 4
See identical proteins and their annotated locations for NP_001243657.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at an alternate start codon, and lacks an in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AF161450, AK295257, BC001384
- Consensus CDS
-
CCDS58716.1
- UniProtKB/TrEMBL
-
B7Z7L9
- Related
- ENSP00000396133.2, ENST00000450066.6
- Conserved Domains (1) summary
-
- cd02669
Location:28 → 450
- Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
-
NM_006590.4 → NP_006581.2 ubiquitin carboxyl-terminal hydrolase 39 isoform 1
See identical proteins and their annotated locations for NP_006581.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same isoform (1).
- Source sequence(s)
-
AK289451, BC001384
- Consensus CDS
-
CCDS33234.1
- UniProtKB/Swiss-Prot
- A8K086, B3KM40, B4DHT4, D6W5L4, G5E9H0, Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310
- UniProtKB/TrEMBL
-
B9A018
- Related
- ENSP00000312981.6, ENST00000323701.11
- Conserved Domains (1) summary
-
- cd02669
Location:106 → 553
- Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
RNA
-
NR_046347.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) uses an alternate 5'-most exon compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AI201523, AK056334, DA548921
- Related
-
ENST00000459775.5