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    Mageb5 MAGE family member B5 [ Mus musculus (house mouse) ]

    Gene ID: 74271, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mageb5provided by MGI
    Official Full Name
    MAGE family member B5provided by MGI
    Primary source
    MGI:MGI:2148169
    See related
    Ensembl:ENSMUSG00000061392 AllianceGenome:MGI:2148169
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mMage-b5; 1700056A17Rik
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including egg cylinder and gonad. Orthologous to human MAGEB5 (MAGE family member B5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 3.0) See more
    Orthologs
    NEW
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    Genomic context

    See Mageb5 in Genome Data Viewer
    Location:
    X C2; X 40.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (90823214..90826582, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (91779608..91782976, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene Gm5941 pseudogene Neighboring gene MAGE family member B17, pseudogene Neighboring gene MAGE family member B5B Neighboring gene STARR-seq mESC enhancer starr_47537 Neighboring gene predicted gene, 46678 Neighboring gene melanoma antigen, family B pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • MGC151150, MGC151152

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    MAGE family member B5
    Names
    melanoma antigen, family B, 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028847.1NP_083123.1  MAGE family member B5

      See identical proteins and their annotated locations for NP_083123.1

      Status: PROVISIONAL

      Source sequence(s)
      BC116775
      Consensus CDS
      CCDS53133.1
      UniProtKB/TrEMBL
      Q14AN0, Q9D9K4
      Related
      ENSMUSP00000080706.3, ENSMUST00000082048.3
      Conserved Domains (2) summary
      pfam01454
      Location:151305
      MAGE; MAGE family
      pfam12440
      Location:580
      MAGE_N; Melanoma associated antigen family N terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      90823214..90826582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)