Marchf9 membrane associated ring-CH-type finger 9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Marchf9provided by MGI
Official Full Name: membrane associated ring-CH-type finger 9provided by MGI
Primary source: MGI:MGI:2446144
See related: Ensembl:ENSMUSG00000040502 AllianceGenome:MGI:2446144
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: March9
Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in Golgi membrane and lysosomal membrane. Predicted to be active in Golgi stack and trans-Golgi network. Is expressed in cortical plate. Orthologous to human MARCHF9 (membrane associated ring-CH-type finger 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in whole brain E14.5 (RPKM 17.3), CNS E18 (RPKM 15.5) and 24 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 D3; 10 74.5 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (126891919..126896053, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (127056050..127060184, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (1)

General gene information

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Markers

PMC212711P1 (e-PCR)
- UniSTS:272025

PMC212738P3 (e-PCR)
- UniSTS:272029

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables ubiquitin-protein transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in Golgi stack	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi stack	ISO Inferred from Sequence Orthology more info
located_in Golgi stack	ISS Inferred from Sequence or Structural Similarity more info
located_in lysosomal membrane	IEA Inferred from Electronic Annotation more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network	ISO Inferred from Sequence Orthology more info
located_in trans-Golgi network	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase MARCHF9

Names: E3 ubiquitin-protein ligase MARCH9; MARCH-IX; RING-type E3 ubiquitin transferase MARCH9; RING-type E3 ubiquitin transferase MARCHF9; membrane-associated RING finger protein 9; membrane-associated RING-CH protein IX; membrane-associated ring finger (C3HC4) 9

NP_001028434.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033262.2 → NP_001028434.1 E3 ubiquitin-protein ligase MARCHF9

See identical proteins and their annotated locations for NP_001028434.1

Status: PROVISIONAL

Source sequence(s)

AK158026

Consensus CDS

CCDS24225.1

UniProtKB/Swiss-Prot

Q3TZ87, Q8VCL1

Related

ENSMUSP00000041581.6, ENSMUST00000040307.6

Conserved Domains (1) summary

smart00744
Location:109 → 155

RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins