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    RIM13 Rim13p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855186, updated on 28-Oct-2024

    Summary

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    Official Symbol
    RIM13
    Official Full Name
    Rim13p
    Primary source
    SGD:S000004763
    Locus tag
    YMR154C
    See related
    AllianceGenome:SGD:S000004763; FungiDB:YMR154C; VEuPathDB:YMR154C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CPL1
    Summary
    Enables cysteine-type endopeptidase activity. Involved in protein processing. Orthologous to human CAPN7 (calpain 7). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See RIM13 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (565999..568182, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Yim1p Neighboring gene FG-nucleoporin NUP53 Neighboring gene uncharacterized protein Neighboring gene polynucleotide 3'-phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The protease activity of a calpain-like cysteine protease in Saccharomyces cerevisiae is required for alkaline adaptation and sporulation. Futai E, et al. Mol Gen Genet, 1999 Jan. PMID 9928935
    2. Rapid turnover of transcription factor Rim101 confirms a flexible adaptation mechanism against environmental stress in Saccharomyces cerevisiae. Obara K, et al. Genes Cells, 2020 Oct. PMID 32741024
    3. Alkaline response genes of Saccharomyces cerevisiae and their relationship to the RIM101 pathway. Lamb TM, et al. J Biol Chem, 2001 Jan 19. PMID 11050096
    4. cis- and trans-acting localization determinants of pH response regulator Rim13 in Saccharomyces cerevisiae. Subramanian S, et al. Eukaryot Cell, 2012 Oct. PMID 22865500, Free PMC Article
    5. The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast. Carmona-Gutierrez D, et al. Cell Cycle, 2013 Jun 1. PMID 23656787, Free PMC Article

    See all (76) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rim13 is associated with the Rim20-ESCRT complex.
      Title: cis- and trans-acting localization determinants of pH response regulator Rim13 in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cysteine-type endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Rim13p
    NP_013875.1
    • Calpain-like cysteine protease; involved in proteolytic activation of Rim101p in response to alkaline pH; localizes to punctate structures in alkaline conditions and in vps4 mutant; has similarity to A. nidulans palB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      565999..568182 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182657.1 → NP_013875.1  TPA: Rim13p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013875.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZX5, Q03792
      UniProtKB/TrEMBL
      A6ZML2, G2WKK5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03792.1

    Gene LinkOut

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