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    FMP41 Fmp41p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855553, updated on 1-Aug-2024

    Summary

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    Gene symbol
    FMP41
    Gene description
    Fmp41p
    Primary source
    FungiDB:YNL168C
    Locus tag
    YNL168C
    See related
    SGD:S000005112; AllianceGenome:SGD:S000005112; VEuPathDB:YNL168C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable acetylpyruvate hydrolase activity. Located in mitochondrion. Orthologous to human FAHD1 (fumarylacetoacetate hydrolase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See FMP41 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (318030..318809, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene anaphase promoting complex subunit 1 Neighboring gene phosphatidylserine decarboxylase 1 Neighboring gene Sko1p Neighboring gene Bni5p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption and basic phenotypic analysis of six novel genes from the left arm of chromosome XIV of Saccharomyces cerevisiae. Dueñas E, et al. Yeast, 1999 Jan 15. PMID 10028186
    2. Global protein expression profiling of budding yeast in response to DNA damage. Lee MW, et al. Yeast, 2007 Mar. PMID 17351896
    3. A genomic analysis of chronological longevity factors in budding yeast. Burtner CR, et al. Cell Cycle, 2011 May 1. PMID 21447998, Free PMC Article
    4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873
    5. The proteome of Saccharomyces cerevisiae mitochondria. Sickmann A, et al. Proc Natl Acad Sci U S A, 2003 Nov 11. PMID 14576278, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables acetylpyruvate hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables oxaloacetate tautomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fmp41p
    NP_014231.1
    • hypothetical protein; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      318030..318809 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183006.1 → NP_014231.1  TPA: Fmp41p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014231.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W114, P53889
      UniProtKB/TrEMBL
      A6ZRR5, B3LP22, B5VQN9, C7GTE5, C8ZG60, G2WLT8, N1NWG6
      Conserved Domains (1) summary
      COG0179
      Location:6 → 233
      MhpD; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport and catabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53889.1

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